SCHEMBL1561622

SCHEMBL1561622

CCCCCCCC[Al](CCCCCCCC)Oc1ccc(OC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
MMP2 P08253 2/20 0.40
MMP9 P14780 2/20 0.40
MMP8 P22894 2/20 0.40
MMP13 P45452 2/20 0.40
CNR1 P21554 3/20 0.39
CNR2 P34972 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
PTGES O14684 2/20 0.38
NR5A1 Q13285 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1560487 0.83 LTA4H (0.46) CNR1NR1I2
SCHEMBL27788476 0.81 LTA4H (0.44) CNR1NR1I2
SCHEMBL2837117 0.81 LTA4H (0.47) CNR1NR1I2
SCHEMBL3677578 0.79 ALDH1A1 (0.50) MGLL
SCHEMBL3689630 0.79 ALDH1A1 (0.50) MGLL
SCHEMBL3681302 0.79 ALDH1A1 (0.50) MGLL
SCHEMBL27788474 0.76 LTA4H (0.43) MMP2MMP9MMP8MMP13CNR1
SCHEMBL9421886 0.76 CA1 (0.52) MAPTCA12CA1CA2CA7
SCHEMBL3681066 0.76 SMN1; SMN2 (0.39) MAPTNPC1RAB9A
SCHEMBL23128627 0.72 NR5A1 (0.68) MAPTNR5A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3009459-B1 OLEFIN POLYMERIZATION PROCESS USING A MODIFIER DOW GLOBAL TECHNOLOGIES LLC (US) 2017-08-02 EP disclosed
EP-3009459-A1 OLEFIN POLYMERIZATION PROCESS USING A MODIFIER Dow Global Technologies LLC (US) 2016-04-20 EP disclosed
CN-103102442-B The method of selective polymerization properties-correcting agent DOW GLOBAL TECHNOLOGIES INC. (US) 2016-01-20 CN disclosed
CN-104892814-A TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS DOW GLOBAL TECHNOLOGIES INC 2015-09-09 CN disclosed
CN-102321201-B Method for selecting polymerization modifiers DOW GLOBAL TECHNOLOGIES INC 2013-06-26 CN disclosed
CN-103102442-A Method for selecting polymerization modifiers Dow Global Technologise LLC 2013-05-15 CN disclosed
US-8383542-B2 Polymerization modifiers DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-02-26 US disclosed
US-8343886-B2 Polymerization modifiers DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-01-01 US disclosed
US-20110196117-A1 POLYMERIZATION MODIFIERS Dow Global Technologise LLC (US) 2011-08-11 US disclosed
US-20110184135-A1 POLYMERIZATION MODIFIERS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-07-28 US disclosed
EP-2345677-A2 Technique for selecting polymerization modifiers Dow Global Technologies LLC (US) 2011-07-20 EP disclosed
US-7943546-B2 Polymerization modifiers DOW GLOBAL TECHNOLOGIES LLC (US) 2011-05-17 US disclosed
EP-1763542-B1 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS DOW GLOBAL TECHNOLOGIES INC (US) 2011-04-06 EP disclosed
US-20090264605-A1 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS CORSS REFERENCE STATEMENT DOW GLOBAL TECHNOLOGIES INC. (US) 2009-10-22 US disclosed
US-7553917-B2 Technique for selecting polymerization modifiers cross reference statement DOW GLOBAL TECHNOLOGIES, INC. (US) 2009-06-30 US disclosed
US-20070219327-A1 Technique for Selecting Polymerization Modifiers Cross Reference Statement DOW GLOBAL TECHNOLOGIES INC. 2007-09-20 US disclosed
EP-1763542-A2 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS CROSS REFERENCE STATEMENT Dow Gloval Technologies Inc. (US) 2007-03-21 EP disclosed
WO-2006007094-A2 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110196117-A1 POLYMERIZATION MODIFIERS ALOX12, MYB, ALOX5 MAPT 1362/4885CA12 3312/4885CA1 4321/4885
US-20090264605-A1 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS CORSS REFERENCE STATEMENT NOTUM, COASY, WASF2 MAPT 575/4885CA12 1332/4885CA1 3056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.