SCHEMBL1561964

SCHEMBL1561964

CC(C)(C)OC(=O)N[C@@H](CO)C(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.59
SYK P43405 1/20 0.56
CTSS P25774 4/20 0.56
CTSK P43235 5/20 0.54
CTSL P07711 1/20 0.54
CTSB P07858 1/20 0.54
PPARG P37231 2/20 0.54
ACE P12821 1/20 0.52
KLK7 P49862 2/20 0.51
KLK5 Q9Y337 2/20 0.51
CACNA1B Q00975 2/20 0.50
ATM Q13315 1/20 0.50
TACR1 P25103 1/20 0.50
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30253476 1.00 PPARA (0.59) PPARASYKCTSSCTSKCTSL
SCHEMBL7172323 1.00 PPARA (0.59) PPARASYKCTSSCTSKCTSL
SCHEMBL1562695 1.00 PPARA (0.59) PPARASYKCTSSCTSKCTSL
SCHEMBL12292883 0.95 PPARA (0.55) PPARASYKCTSSCTSKCTSL
SCHEMBL12294436 0.92 CTSS (0.61) PPARACTSSCTSKCTSLCTSB
SCHEMBL16478621 0.91 ACE (0.55) PPARASYKCTSSCTSKCTSL
SCHEMBL16472131 0.91 ACE (0.55) PPARASYKCTSSCTSKCTSL
SCHEMBL17949815 0.91 ACE (0.55) PPARASYKCTSSCTSKCTSL
SCHEMBL12293283 0.90 CTSK (0.52) PPARASYKCTSSCTSKCTSL
SCHEMBL1094804 0.90 PPARA (0.57) PPARASYKCTSSCTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954987-A Apoptosis bionic nano drug delivery carrier and preparation method and application thereof 暨南大学 2025-05-09 CN claimed
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN claimed
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
US-20260071353-A1 SUBSTRATES, PEPTIDE ARRAYS, AND METHODS VIBRANT HOLDINGS LLC (US) 2026-03-12 US disclosed
WO-2025235719-A1 DIMERIC SMAC MIMETICS USEFUL IN HIV THERAPY VIIV HEALTHCARE COMPANY (US) 2025-11-13 WO disclosed
US-12454771-B2 Substrates, peptide arrays, and methods VIBRANT HOLDINGS LLC (US) 2025-10-28 US disclosed
US-20250263365-A1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-21 US disclosed
EP-3878836-B1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-23 EP disclosed
US-12312297-B2 O-substituted serine derivative production method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-27 US disclosed
CN-119954987-A Apoptosis bionic nano drug delivery carrier and preparation method and application thereof 暨南大学 2025-05-09 CN disclosed
US-12264158-B2 Protein kinase MKK4 inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death HEPAREGENIX GMBH (DE) 2025-04-01 US disclosed
US-5175257-A Radiolabeled proteins for diagnostic or therapeutic use NEORX CORPORATION (US) 1992-12-29 US disclosed
US-5117034-A Phosphatidylserine derivatives FUJI PHOTO FILM CO., LTD. (JP) 1992-05-26 US disclosed
US-5112953-A RADIOLABELED PROTEINS FOR DIAGNOSTIC OR THERAPEUTIC USE NEORX CORPORATION (US) 1992-05-12 US disclosed
EP-0483732-A2 Phosphorylating agent and method for forming phosphodiester bond using the same FUJI PHOTO FILM CO., LTD. (JP) 1992-05-06 EP disclosed
EP-0461245-A1 RADIOLABELED PROTEINS FOR DIAGNOSTIC OR THERAPEUTIC USE NEORX CORPORATION (US) 1991-12-18 EP disclosed
EP-0274234-B1 SPIRO-SUBSITUTED GLUTARAMIDE DIURETIC AGENTS Pfizer Limited (GB) 1991-09-11 EP disclosed
WO-1991009876-A1 RADIOLABELED PROTEINS FOR DIAGNOSTIC OR THERAPEUTIC USE NEORX CORPORATION (US) 1991-07-11 WO disclosed
US-5030654-A Glutaramide diuretic agents PFIZER INC. (US) 1991-07-09 US disclosed
EP-0274234-A2 Spiro-subsituted glutaramide diuretic agents Pfizer Limited (GB) 1988-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071353-A1 SUBSTRATES, PEPTIDE ARRAYS, AND METHODS VIP, CALCB, SPPL2B PPARA 3535/4885SYK 937/4885CTSS 254/4885
US-20250263365-A1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD STS, SMOX, TST PPARA 4142/4885SYK 534/4885CTSS 2594/4885
US-12264158-B2 Protein kinase MKK4 inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death MAPK4, MAP3K4, MAP4K1 PPARA 934/4885SYK 2298/4885CTSS 3550/4885
US-12312297-B2 O-substituted serine derivative production method STS, SMOX, TST PPARA 4142/4885SYK 534/4885CTSS 2594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.