Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13294089 | 0.96 | RELA (0.42) | INSRRAB9AHTTMEN1KMT2A | |
| SCHEMBL3835370 | 0.96 | RELA (0.42) | INSRRAB9AHTTMEN1KMT2A | |
| Bromide SCHEMBL3297144 | 0.95 | INSR (0.41) | INSRRAB9AHTTMEN1KMT2A | |
| SCHEMBL13839773 | 0.84 | INSR (0.34) | INSRRAB9AHTTMEN1KMT2A | |
| SCHEMBL13133372 | 0.75 | RAB9A (0.57) | INSRRAB9AHTTMEN1KMT2A | |
| SCHEMBL3834682 | 0.73 | RAB9A (0.40) | INSRRAB9AHTTMEN1KMT2A | |
| SCHEMBL3834687 | 0.73 | RAB9A (0.40) | INSRRAB9AHTTMEN1KMT2A | |
| SCHEMBL19903920 | 0.72 | KDM4A (0.61) | INSRRAB9AHTTMEN1KMT2A | |
| SCHEMBL13839763 | 0.70 | INSR (0.39) | INSRHTTMEN1KMT2ALMNA | |
| SCHEMBL15624210 | 0.69 | APP (0.47) | INSRRAB9AHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053094-B1 | Composition for dyeing keratinous fibres comprising at least one direct dye with disulphur/thiol function and at least one polymer with thiol function and method using the composition | OREAL (FR) | 2014-03-26 | — | — | EP | disclosed |