Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSS | P25774 | 7/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17002536 | 0.90 | CTSS (0.43) | CTSKCTSSCAPN1F10MEN1 | |
| SCHEMBL19788373 | 0.90 | CTSK (0.46) | CTSKCTSSCAPN1F10MEN1 | |
| SCHEMBL13331674 | 0.89 | CTSK (0.49) | CTSKCTSSCAPN1MEN1GAA | |
| SCHEMBL29711843 | 0.88 | CTSK (0.52) | CTSKCTSSCAPN1F10MEN1 | |
| SCHEMBL29711719 | 0.85 | CTSS (0.45) | CTSKCTSSCAPN1F10MEN1 | |
| SCHEMBL25469335 | 0.83 | MEN1 (0.49) | CTSKCTSSCAPN1MEN1GAA | |
| SCHEMBL23728734 | 0.82 | CTSK (0.50) | CTSKCTSSCAPN1MEN1GAA | |
| SCHEMBL29734569 | 0.82 | CTSK (0.50) | CTSKCTSSCAPN1MEN1GAA | |
| SCHEMBL23728735 | 0.82 | CTSK (0.50) | CTSKCTSSCAPN1MEN1GAA | |
| SCHEMBL25696029 | 0.82 | CTSK (0.50) | CTSKCTSSCAPN1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160184459-A1 | CANCER CELL SPECIFIC IMAGING PROBES AND METHODS OF USE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-06-30 | — | — | US | disclosed |
| US-20150224208-A1 | NOVEL PRODRUGS FOR SELECTIVE ANTICANCER THERAPY | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2015-08-13 | — | — | US | disclosed |
| WO-2014047199-A1 | NOVEL PRODRUGS FOR SELECTIVE ANTICANCER THERAPY | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184459-A1 | CANCER CELL SPECIFIC IMAGING PROBES AND METHODS OF USE | OR10J3, CCR3, GPR3 | CTSK 4641/4885CTSS 4685/4885CAPN1 4622/4885 |
| US-20150224208-A1 | NOVEL PRODRUGS FOR SELECTIVE ANTICANCER THERAPY | NR4A3, ORC3, NTSR1 | CTSK 3687/4885CTSS 3296/4885CAPN1 3663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.