Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834548 | 1.00 | F10 (0.54) | F10PTGS2AKR1C3 | |
| SCHEMBL76558 | 0.84 | F10 (0.58) | F10PTGS2 | |
| SCHEMBL28956907 | 0.82 | PTGS2 (0.67) | F10PTGS2 | |
| SCHEMBL2540317 | 0.82 | F10 (0.54) | F10PTGS2 | |
| SCHEMBL19086541 | 0.82 | PTGS2 (0.64) | F10PTGS2 | |
| SCHEMBL18630668 | 0.82 | F10 (0.54) | F10PTGS2AKR1C3 | |
| SCHEMBL92872 | 0.82 | PTGS2 (0.64) | F10PTGS2AKR1C3 | |
| SCHEMBL15846877 | 0.82 | F10 (0.54) | F10PTGS2 | |
| SCHEMBL19456 | 0.82 | PTGS2 (0.64) | F10PTGS2AKR1C3 | |
| SCHEMBL198132 | 0.81 | PTGS2 (0.57) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016975-B | preparation method of rivaroxaban | 深圳翰宇药业股份有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-104016975-A | Preparation method of rivaroxaban | SHENZHEN HYBIO PHARMACEUTICAL | 2014-09-03 | — | — | CN | claimed |
| EP-3689871-B1 | 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE | SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |
| EP-3689871-A1 | 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |
| CN-105384739-B | Pyrazolo [3,4-c ] pyridine derivatives | 石药集团中奇制药技术（石家庄）有限公司 | 2020-03-20 | — | — | CN | disclosed |
| CN-105777732-B | A kind of synthetic method and its application of Rivaroxaban intermediate | 深圳翰宇药业股份有限公司 | 2019-03-19 | — | — | CN | disclosed |
| CN-104016975-B | preparation method of rivaroxaban | 深圳翰宇药业股份有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-104016975-B | preparation method of rivaroxaban | 深圳翰宇药业股份有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-105777732-A | Method for synthesizing Rivaroxaban intermediate and application of method | 深圳翰宇药业股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105777732-A | Method for synthesizing Rivaroxaban intermediate and application of method | 深圳翰宇药业股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-104016975-A | Preparation method of rivaroxaban | SHENZHEN HYBIO PHARMACEUTICAL | 2014-09-03 | — | — | CN | disclosed |
| CN-104016975-A | Preparation method of rivaroxaban | SHENZHEN HYBIO PHARMACEUTICAL | 2014-09-03 | — | — | CN | disclosed |
| WO-2014044107-A1 | PYRAZOL[3,4-C] PYRIDINE DERIVATIVE, PREPARATION METHOD AND USE IN MEDICINE THEREOF | 上海恒瑞医药有限公司 (CN) | 2014-03-27 | — | — | WO | disclosed |
| WO-2014044113-A1 | PYRAZOL[3,4-C] PYRIDINE DERIVATIVE, PREPARATION METHOD AND USE IN MEDICINE THEREOF | 上海恒瑞医药有限公司 (CN) | 2014-03-27 | — | — | WO | disclosed |