SCHEMBL76558

SCHEMBL76558

Nc1ccc(N2CCOCC2=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F10 P00742 4/20 0.58
PTGS2 P35354 14/20 0.54
TNKS O95271 1/20 0.44
DDB1 Q16531 1/20 0.43
CRBN Q96SW2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75939 0.89 F10 (0.49) F10PTGS2DDB1CRBN
SCHEMBL28956907 0.84 PTGS2 (0.67) F10PTGS2
SCHEMBL28834548 0.84 F10 (0.54) F10PTGS2
SCHEMBL19086541 0.84 PTGS2 (0.64) F10PTGS2
SCHEMBL19456 0.84 PTGS2 (0.64) F10PTGS2
SCHEMBL15846877 0.84 F10 (0.54) F10PTGS2
SCHEMBL92872 0.84 PTGS2 (0.64) F10PTGS2
SCHEMBL15628319 0.84 F10 (0.54) F10PTGS2
SCHEMBL2540317 0.84 F10 (0.54) F10PTGS2
SCHEMBL18630668 0.84 F10 (0.54) F10PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1061 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312320-B2 Method for synthesizing n-substituted phenyl-5-hydroxymethyl-2-oxazolidinone HANGZHOU DIKE TECHNOLOGIES CO., LTD. (CN) 2025-05-27 US claimed
CN-115490678-B Preparation method of high-purity rivaroxaban 浙江苏泊尔制药有限公司 2025-02-18 CN claimed
CN-115260117-B Synthesis method of 4- (4-aminophenyl) morpholin-3-one 江苏法安德医药科技有限公司 2024-05-28 CN claimed
CN-115490678-A Preparation method of high-purity rivaroxaban 浙江苏泊尔制药有限公司 2022-12-20 CN claimed
CN-115260117-A Synthesis method of 4- (4-aminophenyl) morpholine-3-one 江苏法安德医药科技有限公司 2022-11-01 CN claimed
CN-115215854-A Preparation process of efficient rivaroxaban bulk drug 湖南恒生制药股份有限公司 2022-10-21 CN claimed
US-20220267284-A1 METHOD FOR SYNTHESIZING N-SUBSTITUTED PHENYL-5-HYDROXYMETHYL-2-OXAZOLIDINONE HANGZHOU DIKE TECHNOLOGIES CO., LTD. (CN) 2022-08-25 US claimed
CN-112409286-B Synthesis method of N-substituted phenyl-5-hydroxymethyl-2-oxazolidinone 杭州迪克科技有限公司 2022-08-05 CN claimed
CN-114750054-A Polishing device and polishing method for integrated display screen 长沙埃福思科技有限公司 2022-07-15 CN claimed
CN-114752306-A Ferromagnetic polishing solution for integrated display screen and preparation method thereof 长沙埃福思科技有限公司 2022-07-15 CN claimed
US-20040235824-A1 Indazole-derivatives as factor Xa inhibitors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-11-25 US claimed
WO-2004101556-A1 INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-11-25 WO claimed
WO-2004101553-A1 BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-11-25 WO claimed
EP-1479676-A1 Benzimidazole-derivatives as factor xa inhibitors Aventis Pharma Deutschland GmbH (DE) 2004-11-24 EP claimed
EP-1479675-A1 Indazole-derivatives as factor Xa inhibitors Aventis Pharma Deutschland GmbH (DE) 2004-11-24 EP claimed
US-20040204406-A1 Pyrazole-derivatives as factor Xa inhibitors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-10-14 US claimed
WO-2004087646-A2 PYRROLIDINO-1,2-DICARBOXY-1-(PHENYLAMIDE)-2-(4-(3-OXO-MORPHOLINO-4-YL)-PHENYLAMIDE) DERIVATIVES AND RELATED COMPOUNDS FOR USE AS INHIBITORS OF COAGULATION FACTOR XA IN THE TREATMENT OF THROMBO-EMBOLIC DISEASES MERCK PATENT GMBH (DE) 2004-10-14 WO claimed
WO-2004060887-A1 METHOD FOR PRODUCING 5-CHLORO-N-({5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)-PHENYL]-1,3-OXAZOLIDIN-5-YL}-METHYL)-2-THIOPHENE CARBOXAMIDE BAYER HEALTHCARE AG (DE) 2004-07-22 WO claimed
WO-2004056815-A1 PYRAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-07-08 WO claimed
WO-2004017963-A1 BENZIMIDAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2004-03-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040204406-A1 Pyrazole-derivatives as factor Xa inhibitors F11, F5, F12 F10 11/4885PTGS2 919/4885TNKS 1481/4885
US-20220267284-A1 METHOD FOR SYNTHESIZING N-SUBSTITUTED PHENYL-5-HYDROXYMETHYL-2-OXAZOLIDINONE CYP3A5, CYP1A2, CYP3A4 F10 549/4885PTGS2 1027/4885TNKS 1619/4885
US-12312320-B2 Method for synthesizing n-substituted phenyl-5-hydroxymethyl-2-oxazolidinone CYP3A5, CYP1A2, CYP3A4 F10 549/4885PTGS2 1027/4885TNKS 1619/4885
US-20040235824-A1 Indazole-derivatives as factor Xa inhibitors F11, F12, F5 F10 14/4885PTGS2 456/4885TNKS 967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.