SCHEMBL15846877

SCHEMBL15846877

O=C1COCCN1c1ccc([AsH2])cc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.54
PTGS2 P35354 14/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76558 0.84 F10 (0.58) F10PTGS2
SCHEMBL28956907 0.82 PTGS2 (0.67) F10PTGS2
SCHEMBL92872 0.82 PTGS2 (0.64) F10PTGS2
SCHEMBL19086541 0.82 PTGS2 (0.64) F10PTGS2
SCHEMBL2540317 0.82 F10 (0.54) F10PTGS2
SCHEMBL19456 0.82 PTGS2 (0.64) F10PTGS2
SCHEMBL18630668 0.82 F10 (0.54) F10PTGS2
SCHEMBL28834548 0.82 F10 (0.54) F10PTGS2
SCHEMBL15628319 0.82 F10 (0.54) F10PTGS2
SCHEMBL198132 0.81 PTGS2 (0.57) F10PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2897619-A2 ALDEHYDE DERIVATIVE OF SUBSTITUTE OXAZOLIDINONES Wanbury Limited (IN) 2015-07-29 EP disclosed
WO-2014102822-A2 ALDEHYDE DERIVATIVE OF SUBSTITUTE OXAZOLIDINONES WANBURY LTD. (IN) 2014-07-03 WO disclosed