SCHEMBL19086541

SCHEMBL19086541

O=C1COCCN1c1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 11/20 0.64
F10 P00742 9/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76558 0.84 F10 (0.58) PTGS2F10
SCHEMBL18630668 0.82 F10 (0.54) PTGS2F10
SCHEMBL15628319 0.82 F10 (0.54) PTGS2F10
SCHEMBL28834548 0.82 F10 (0.54) PTGS2F10
SCHEMBL15846877 0.82 F10 (0.54) PTGS2F10
SCHEMBL92872 0.82 PTGS2 (0.64) PTGS2F10
SCHEMBL19456 0.82 PTGS2 (0.64) PTGS2F10
SCHEMBL2540317 0.82 F10 (0.54) PTGS2F10
SCHEMBL28956907 0.82 PTGS2 (0.67) PTGS2F10
SCHEMBL198132 0.81 PTGS2 (0.57) PTGS2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3190104-B1 QUINOLINONE COMPOUND AND USE THEREOF SUNSHINE LAKE PHARMA CO LTD (CN) 2021-10-27 EP disclosed
US-10065928-B2 Quinolinone compound and use thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2018-09-04 US disclosed
US-20170247332-A1 QUINOLINONE COMPOUND AND USE THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2017-08-31 US disclosed
EP-3190104-A1 QUINOLINONE COMPOUND AND USE THEREOF Sunshine Lake Pharma Co., Ltd. (CN) 2017-07-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170247332-A1 QUINOLINONE COMPOUND AND USE THEREOF HIF1AN, HIF1A, EGLN2 PTGS2 52/4885F10 1853/4885
US-10065928-B2 Quinolinone compound and use thereof HIF1AN, HIF1A, EGLN2 PTGS2 52/4885F10 1853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.