SCHEMBL1563396

SCHEMBL1563396

C=CC(=O)N(C)C(O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
BCL2A1 Q16548 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL2438446 0.94 BCL2A1 (0.30) BCL2A1
SCHEMBL9283699 0.86 CA1 (0.33)
SCHEMBL27695608 0.77 TSHR (0.33) LMNATP53ALDH1A1BCL2A1
SCHEMBL541432 0.77 TSHR (0.33) LMNATP53ALDH1A1BCL2A1
SCHEMBL17665961 0.77 TSHR (0.33) LMNATP53ALDH1A1BCL2A1
SCHEMBL194055 0.77 MEN1 (0.33) BCL2A1
SCHEMBL515482 0.76 LMNA (0.36) LMNA
SCHEMBL646634 0.76
SCHEMBL28540822 0.74 ADAMTS4 (0.33) LMNABCL2A1
SCHEMBL31153748 0.74 ADAMTS4 (0.33) LMNABCL2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3515993-A1 METHOD FOR PRODUCING A WATER-SOLUBLE THERMALLY-CROSSLINKABLE POLYMERIC MATERIAL Novartis AG (CH) 2019-07-31 EP claimed
WO-2018055488-A1 METHOD FOR PRODUCING A WATER-SOLUBLE THERMALLY-CROSSLINKABLE POLYMERIC MATERIAL NOVARTIS AG (CH) 2018-03-29 WO claimed
US-20180079889-A1 METHOD FOR PRODUCING A WATER-SOLUBLE THERMALLY-CROSSLINKABLE POLYMERIC MATERIAL ALCON INC. (CH) 2018-03-22 US claimed
EP-2431396-B1 Vinyl acetate based alkaline resistant scrim binder CELANESE SALES GERMANY GMBH (DE) 2016-07-27 EP claimed
EP-1153979-B2 Functionalised copolymers for the preparation of coating materials WACKER CHEMIE AG (DE) 2011-04-06 EP claimed
EP-0929844-B1 ANTIREFLECTIVE COATING FOR PHOTORESIST COMPOSITIONS CLARIANT FINANCE BVI LTD (VG) 2001-12-12 EP claimed
EP-0651033-B1 Expandable coating composition ROHM & HAAS (US) 1999-09-01 EP claimed
US-5496896-A Curable composition based on a Michael addition product, processes for its preparation and its use BASF LACKE & FARBEN AKTIENGESELLSCHAFT (DE) 1996-03-05 US claimed
US-5478641-A Cellulose material containing cured emulsion copolymer in the form of solid GENCORP INC. (US) 1995-12-26 US claimed
EP-0387511-B1 Formaldehyde-free heat resistant binders for nonwovens NAT STARCH CHEM INVEST (US) 1994-08-31 EP claimed
EP-0361048-B1 CURABLE COMPOSITION CONTAINING A MICHAEL ADDITION PRODUCT, ITS PREPARATION AND ITS USE BASF Lacke + Farben AG (DE) 1993-05-26 EP claimed
EP-0287842-B1 CURABLE COMPOSITIONS CONTAINING A MICHAEL-ADDITION PRODUCT, THEIR PREPARATION AND USE BASF Lacke + Farben AG (DE) 1991-06-12 EP claimed
EP-0276213-B1 SOLUBLE CROSS-LINKABLE ACRYLATE COPOLYMERIZATE, PROCESS FOR ITS MANUFACTURE AND APPLICATION PRODUCT BASED ON SAID ACRYLATE COPOLYMERIZATE BASF Lacke + Farben AG (DE) 1990-08-01 EP claimed
EP-4396617-A1 A METHOD FOR PRODUCING WETTABLE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-07-10 EP disclosed
EP-3724696-B1 WEEKLY AND MONTHLY DISPOSABLE WATER GRADIENT CONTACT LENSES ALCON INC (CH) 2024-07-03 EP disclosed
US-20240176047-A1 WEEKLY AND MONTHLY DISPOSABLE WATER GRADIENT CONTACT LENSES ALCON INC. (CH) 2024-05-30 US disclosed
US-5061523-A COATING STEELS HENKEL CORPORATION (US) 1991-10-29 US disclosed
US-4778869-A COATINGS, ADHESIVES, MOLDINGS AMERICAN CYANAMID COMPANY (US) 1988-10-18 US disclosed
US-4656308-A COATINGS AMERICAN CYANAMID COMPANY (US) 1987-04-07 US disclosed
EP-0020000-A1 Activated ester monomers, polymers formed therefrom and coating compositions containing said polymers AMERICAN CYANAMID COMPANY (US) 1980-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180079889-A1 METHOD FOR PRODUCING A WATER-SOLUBLE THERMALLY-CROSSLINKABLE POLYMERIC MATERIAL INCENP, ILK, HSF1 LMNA 2323/4885TP53 2111/4885ALDH1A1 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.