SCHEMBL515482

SCHEMBL515482

C=CC(=O)N(C(=O)C=C)C(O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1563396 0.76 LMNA (0.33) LMNA
SCHEMBL30879932 0.73 ALDH1A1 (0.39) TSHR
SCHEMBL28890381 0.73 PTGS1 (0.33) LMNA
SCHEMBL9285153 0.73 OR51E2 (0.31) LMNA
SCHEMBL9895413 0.73 PTGS1 (0.33) LMNA
SCHEMBL5698301 0.72 TSHR (0.37) LMNATSHR
SCHEMBL7212046 0.72 LMNA (0.35) LMNA
SCHEMBL2532101 0.72 ALDH1A1 (0.33) TSHR
Methoxymethane SCHEMBL2438446 0.72 BCL2A1 (0.30)
SCHEMBL18527055 0.69 TSHR (0.39) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3724696-B1 WEEKLY AND MONTHLY DISPOSABLE WATER GRADIENT CONTACT LENSES ALCON INC (CH) 2024-07-03 EP claimed
US-20240176047-A1 WEEKLY AND MONTHLY DISPOSABLE WATER GRADIENT CONTACT LENSES ALCON INC. (CH) 2024-05-30 US claimed
US-11933941-B2 Weekly and monthly disposable water gradient contact lenses ALCON INC. (CH) 2024-03-19 US claimed
EP-3724699-B1 METHOD FOR PRODUCING MPS-COMPATIBLE WATER GRADIENT CONTACT LENSES ALCON INC (CH) 2023-07-26 EP claimed
EP-2788797-B1 CONTACT LENSES WITH ENZYMATICALLY DEGRADABLE COATINGS THEREON ALCON INC (CH) 2023-06-07 EP claimed
US-20220137263-A1 WEEKLY AND MONTHLY DISPOSABLE WATER GRADIENT CONTACT LENSES ALCON INC. (CH) 2022-05-05 US claimed
US-11256003-B2 Weekly and monthly disposable water gradient contact lenses ALCON INC. (CH) 2022-02-22 US claimed
EP-3724697-B1 METHOD FOR PRODUCING MPS-COMPATIBLE WATER GRADIENT CONTACT LENSES ALCON INC (CH) 2022-01-12 EP claimed
US-11061168-B2 Silicone hydrogel lens with a crosslinked hydrophilic coating ALCON INC. (CH) 2021-07-13 US claimed
US-11029447-B2 Method for producing MPS-compatible water gradient contact lenses ALCON INC. (CH) 2021-06-08 US claimed
US-8529057-B2 Silicone hydrogel lens with a crosslinked hydrophilic coating NOVARTIS AG (CH) 2013-09-10 US claimed
WO-2013086119-A2 CONTACT LENSES WITH ENZYMATICALLY DEGRADABLE COATINGS THEREON NOVARTIS AG (CH) 2013-06-13 WO claimed
US-20130148077-A1 CONTACT LENSES WITH ENZYMATICALLY DEGRADABLE COATINGS THEREON NOVARTIS AG (CH) 2013-06-13 US claimed
EP-2598938-A1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING Novartis AG (CH) 2013-06-05 EP claimed
WO-2013074535-A1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING NOVARTIS AG (CH) 2013-05-23 WO claimed
US-20130118127-A1 SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING NOVARTIS AG (CH) 2013-05-16 US claimed
US-20130095235-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES NOVARTIS AG (CH) 2013-04-18 US claimed
WO-2013055746-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES BY COATING NOVARTIS AG (CH) 2013-04-18 WO claimed
US-20120026457-A1 SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING ALCON INC. (CH) 2012-02-02 US claimed
WO-2012016098-A1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING NOVARTIS AG (CH) 2012-02-02 WO claimed