Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Thioglycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thioglycolic Acid SCHEMBL15768801 | 0.96 | — | — | |
| Thioglycolic Acid SCHEMBL329120 | 0.96 | CA4 (0.44) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Thioglycolic Acid SCHEMBL10795892 | 0.92 | CA4 (0.47) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Thioglycolic Acid SCHEMBL4274828 | 0.92 | — | — | |
| Thioglycolic Acid SCHEMBL1275216 | 0.92 | CA4 (0.47) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Thioglycolic Acid SCHEMBL216244 | 0.92 | CA4 (0.47) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Thioglycolic Acid SCHEMBL692043 | 0.92 | CA4 (0.47) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Thioglycolic Acid SCHEMBL59723 | 0.92 | — | — | |
| Thioglycolic Acid SCHEMBL8897741 | 0.92 | CA4 (0.47) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Thioglycolic Acid SCHEMBL16760982 | 0.92 | CA4 (0.47) | CA4CASP1FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3333 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120767490-B | Echelon battery energy storage system based on water cooling heat dissipation and comprehensive environment monitoring | 南京禄口国际机场空港科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122065064-A | Ship track clustering method integrating multidimensional features | 武汉理工大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122048148-A | River basin water quantity scheduling scheme toughness evaluation method based on multidimensional index | 黄河水利委员会黄河水利科学研究院 | 2026-05-15 | — | — | CN | claimed |
| US-20260008607-A1 | METERED DOSAGE APPARATUS | THE SALFORD VALVE COMPANY LTD (GB) | 2026-01-08 | — | — | US | claimed |
| US-12458576-B2 | Method for removing color from artificially colored hair | L'OREAL (FR) | 2025-11-04 | — | — | US | claimed |
| US-12364656-B2 | Depilatory compositions comprising aminoalkylpropanol | Reckitt Benckiser Health Limited (GB) | 2025-07-22 | — | — | US | claimed |
| EP-4582354-A1 | METERED DOSAGE APPARATUS | The Salford Valve Company Limited (GB) | 2025-07-09 | — | — | EP | claimed |
| CN-119669501-B | Design method, system, equipment and medium for ancient folk house woodcarving window patterns | 南昌大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120146652-A | AKFCM model-based comprehensive evaluation method for power distribution automation terminal state | 国网辽宁省电力有限公司鞍山供电公司 | 2025-06-13 | — | — | CN | claimed |
| CN-120128512-A | Block chain consensus protocol selection method based on fuzzy multi-criterion decision | 重庆邮电大学 | 2025-06-10 | — | — | CN | claimed |
| US-4981682-A | MERCAPTOCARBOXYLCI ACID, TERTIARY AMINE | THE BOOTS COMPANY PLC (GB) | 1991-01-01 | — | — | US | claimed |
| EP-0215735-B1 | VETERINARY-MEDICAL KIT FOR A RAPID TEST TO DETERMINE THE CALCIUM CONTENT OF BLOOD | Dr. Ernst Gräub AG (CH) | 1990-06-13 | — | — | EP | claimed |
| US-4923478-A | DEPILATORIES, SODIUM STEARATE, PROPYLENE GLYCOL, THIOGLYCOLIC ACID SALT | CARTER-WALLACE, INC. (US) | 1990-05-08 | — | — | US | claimed |
| EP-0360579-A1 | UV curable compositions for making solder mask coating | M & T CHEMICALS, INC. (US) | 1990-03-28 | — | — | EP | claimed |
| EP-0307129-A1 | Depilatory compositions | The Boots Company PLC (GB) | 1989-03-15 | — | — | EP | claimed |
| EP-0215735-A1 | Veterinary-medical kit for a rapid test to determine the calcium content of blood | Dr. Ernst Gräub AG (CH) | 1987-03-25 | — | — | EP | claimed |
| EP-0178931-A1 | Composition for cleaning drains | GENEX CORPORATION (US) | 1986-04-23 | — | — | EP | claimed |
| US-4540506-A | PROTEOLYTIC ENZYME, DISULFIDE REDUCING AGENT | GENEX CORPORATION (US) | 1985-09-10 | — | — | US | claimed |
| US-4121904-A | THIOGLYCOLATES | ALBERTO-CULVER COMPANY (US) | 1978-10-24 | — | — | US | claimed |
| US-3981681-A | Depilatory formulation | CARSON PRODUCTS COMPANY (US) | 1976-09-21 | — | — | US | claimed |