Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 2/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15646950 | 0.76 | CDK5 (0.44) | ALDH1A1CDK5CDK5R1PRMT5WDR77 | |
| SCHEMBL28018180 | 0.72 | ALDH1A1 (0.46) | GPR119KMT2AGAAHPGDALDH1A1 | |
| SCHEMBL15645841 | 0.69 | CPT1A (0.40) | GPR119CPT1ACPT2ALDH1A1CDK5 | |
| SCHEMBL7520610 | 0.68 | KMT2A (0.46) | KMT2AGAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL31246080 | 0.68 | PRKCB (0.35) | GPR119GAA | |
| SCHEMBL22264544 | 0.67 | HSD17B10 (0.45) | KMT2AHPGDALDH1A1SMN1; SMN2PREP | |
| SCHEMBL19617917 | 0.66 | GPR119 (0.38) | GPR119KMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL31732979 | 0.66 | GPR119 (0.38) | GPR119KMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL23043680 | 0.66 | CHRNB2 (0.35) | GPR119 | |
| SCHEMBL29806270 | 0.66 | ALDH1A1 (0.41) | CPT1ACPT2ALDH1A1SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014062938-A1 | RORY MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-04-24 | — | — | WO | disclosed |