Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138022 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL1177696 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL181277 | 0.81 | MME (0.51) | MMEMMP2CTRB1HPGDCYP3A4 | |
| SCHEMBL18577077 | 0.81 | MME (0.47) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL18577075 | 0.81 | MME (0.47) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL11884009 | 0.77 | CTRB1 (0.49) | MMEMMP2CTRB1OPRM1CYP3A4 | |
| SCHEMBL995228 | 0.76 | ALDH1A1 (0.64) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL995229 | 0.76 | ALDH1A1 (0.64) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL6293500 | 0.76 | ALDH1A1 (0.64) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL2636079 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701684-B2 | Chiral fluorinating reagents | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2015-10-08 | — | — | US | disclosed |
| EP-2914582-A2 | CHIRAL FLUORINATING REAGENTS | Isis Innovation Limited (GB) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014068341-A2 | CHIRAL FLUORINATING REAGENTS | ISIS INNOVATION LIMITED (GB) | 2014-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | TIAM1, AFF2, AFF1 | ALDH1A1 800/4885HTT 2700/4885NCOA1 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.