Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615096 | 0.94 | TSHR (0.37) | TSHRDPP4ALDH1A1CYP2C19 | |
| SCHEMBL6913846 | 0.81 | DPP4 (0.40) | TSHRDPP4ALDH1A1CYP2C19 | |
| SCHEMBL9788184 | 0.78 | TSHR (0.33) | TSHRDPP4ALDH1A1 | |
| SCHEMBL17464907 | 0.74 | TSHR (0.40) | TSHRCYP2C19 | |
| SCHEMBL11654287 | 0.73 | DPP4 (0.35) | TSHRDPP4ALDH1A1CYP2C19 | |
| SCHEMBL765917 | 0.73 | DPP4 (0.35) | TSHRDPP4ALDH1A1CYP2C19 | |
| SCHEMBL20224768 | 0.73 | DPP4 (0.35) | TSHRDPP4ALDH1A1CYP2C19 | |
| SCHEMBL1371359 | 0.72 | ALDH1A1 (0.39) | TSHRDPP4ALDH1A1 | |
| SCHEMBL9788217 | 0.71 | DPP4 (0.33) | TSHRDPP4 | |
| SCHEMBL27145591 | 0.70 | ALDH1A1 (0.38) | TSHRDPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140120058-A1 | POLYMER CONJUGATED PROSTAGLANDIN ANALOGUES | POLYACTIVA PTY LTD | 2014-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140120058-A1 | POLYMER CONJUGATED PROSTAGLANDIN ANALOGUES | PTGIS, PTGS2, PTGES | TSHR 2675/4885DPP4 3976/4885ALDH1A1 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.