Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31688976 | 0.81 | AXL (0.47) | AXLNUDT1AHRRENGRM5 | |
| SCHEMBL17123043 | 0.80 | MMP2 (0.46) | KDM4ESMN1; SMN2TP53LMNACCR1 | |
| SCHEMBL30008044 | 0.80 | PRKCI (0.45) | PRKCIKDM4ESMN1; SMN2TP53LMNA | |
| SCHEMBL31492457 | 0.78 | AHR (0.60) | AHRRENKEAP1 | |
| SCHEMBL30741488 | 0.77 | AHR (0.43) | AXLNUDT1AHRRENKEAP1 | |
| SCHEMBL26260016 | 0.75 | KDM4E (0.58) | KDM4ESMN1; SMN2TP53LMNAL3MBTL1 | |
| SCHEMBL23098933 | 0.75 | PRKCI (0.46) | PRKCIKDM4ESMN1; SMN2TP53LMNA | |
| SCHEMBL31319703 | 0.75 | CCR1 (0.46) | PRKCIKDM4ESMN1; SMN2TP53LMNA | |
| Quinoline SCHEMBL27719790 | 0.74 | ALDH1A1 (0.50) | POLBAXLNUDT1AHRNPC1 | |
| SCHEMBL27924279 | 0.74 | KDM4E (0.65) | PRKCIKDM4ESMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731990-B2 | Carbazole-based Bodipys for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-08-22 | — | — | US | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-3621971-B1 | CARBAZOLE-BASED BODIPYS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-06-23 | — | — | EP | disclosed |
| US-20210079024-A1 | CARBAZOLE-BASED BODIPYS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-03-18 | — | — | US | disclosed |
| US-20150280147-A1 | AROMATIC AZA-BICYCLIC COMPOUNDS CONTAINING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-10-01 | — | — | US | disclosed |
| US-20150280147-A1 | AROMATIC AZA-BICYCLIC COMPOUNDS CONTAINING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-10-01 | — | — | US | disclosed |
| WO-2014067598-A1 | AROMATIC AZA-BICYCLIC COMPOUNDS COMPRISING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210079024-A1 | CARBAZOLE-BASED BODIPYS FOR ORGANIC ELECTROLUMINESCENT DEVICES | CYP1B1, ECI1, FIS1 | PRKCI 3354/4885KDM4E 3933/4885SMN1; SMN2 4190/4885 |
| US-20150280147-A1 | AROMATIC AZA-BICYCLIC COMPOUNDS CONTAINING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES | AOC2, AOC1, AOC3 | PRKCI 4531/4885KDM4E 1180/4885SMN1; SMN2 3932/4885 |
| US-11731990-B2 | Carbazole-based Bodipys for organic electroluminescent devices | CYP1B1, ECI1, FIS1 | PRKCI 3354/4885KDM4E 3933/4885SMN1; SMN2 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.