SCHEMBL15713616

SCHEMBL15713616

Nc1c(Br)ccc(Br)c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
GLA P06280 1/20 0.42
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
KMT2A Q03164 4/20 0.35
GFER P55789 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
MAPT P10636 4/20 0.34
MEN1 O00255 2/20 0.34
POLB P06746 2/20 0.34
THRB P10828 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
CASP6 P55212 2/20 0.34
USP2 O75604 1/20 0.34
PKM P14618 1/20 0.34
APEX1 P27695 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2953687 0.85 CASP7 (0.44) KDM4EGLACA12CA1CA2
SCHEMBL19729201 0.83 KDM4E (0.38) KDM4EGLAKMT2AMAPTPOLB
SCHEMBL31728915 0.83 KDM4E (0.37) KDM4EGLACA12CA1CA2
SCHEMBL30762392 0.83 KDM4E (0.38) KDM4EGLAKMT2AMAPTPOLB
SCHEMBL19816015 0.83 KDM4E (0.37) KDM4EGLACA12CA1CA2
SCHEMBL7777986 0.83 DPP4 (0.50) KDM4EGLAKMT2AMAPTMEN1
SCHEMBL1571423 0.83 CES2 (0.35) KDM4EGLACA12CA1CA2
SCHEMBL7781012 0.83 DPP4 (0.45) KDM4EGLACA12CA1CA2
SCHEMBL10415958 0.82 CA12 (0.43) KDM4EGLACA12CA1CA2
SCHEMBL30474626 0.82 CA12 (0.43) KDM4EGLACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11305999-B2 Graphene nanoribbon precursor and method for producing graphene nanoribbon FUJITSU LIMITED (JP) 2022-04-19 US disclosed
EP-3715322-B1 GRAPHENE NANORIBBON PRECURSOR AND METHOD FOR PRODUCING GRAPHENE NANORIBBON FUJITSU LTD (JP) 2022-03-16 EP disclosed
US-20200308004-A1 GRAPHENE NANORIBBON PRECURSOR AND METHOD FOR PRODUCING GRAPHENE NANORIBBON FUJITSU LIMITED (JP) 2020-10-01 US disclosed
EP-3715322-A1 GRAPHENE NANORIBBON PRECURSOR AND METHOD FOR PRODUCING GRAPHENE NANORIBBON FUJITSU LIMITED (JP) 2020-09-30 EP disclosed
EP-3715322-A1 GRAPHENE NANORIBBON PRECURSOR AND METHOD FOR PRODUCING GRAPHENE NANORIBBON FUJITSU LIMITED (JP) 2020-09-30 EP disclosed
CN-107556319-B Organic electroluminescent compound material and organic electroluminescent device using the same 机光科技股份有限公司 2020-06-23 CN disclosed
US-10186668-B2 Organic electroluminescent material and use thereof LUMINESCENCE TECHNOLOGY CORP. (TW) 2019-01-22 US disclosed
US-20180254415-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND USE THEREOF LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2018-09-06 US disclosed
CN-107556319-A Organic electroluminescent compound material and organic electroluminescent device using the same 机光科技股份有限公司 2018-01-09 CN disclosed
US-9701638-B2 Therapeutic hydroxyquinolones RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-07-11 US disclosed
US-9701638-B2 Therapeutic hydroxyquinolones RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-07-11 US disclosed
US-20170081192-A1 ORTHO-TERPHENYLS FOR THE PREPARATION OF GRAPHENE NANORIBBONS BASF SE (DE) 2017-03-23 US disclosed
US-20170081192-A1 ORTHO-TERPHENYLS FOR THE PREPARATION OF GRAPHENE NANORIBBONS BASF SE (DE) 2017-03-23 US disclosed
WO-2015173215-A1 ORTHO-TERPHENYLS FOR THE PREPARATION OF GRAPHENE NANORIBBONS BASF SE (DE) 2015-11-19 WO disclosed
US-20150291531-A1 THERAPEUTIC HYDROXYQUINOLONES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-10-15 US disclosed
US-20150291531-A1 THERAPEUTIC HYDROXYQUINOLONES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-10-15 US disclosed
WO-2014074926-A1 THERAPEUTIC HYDROXYQUINOLONES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2014-05-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291531-A1 THERAPEUTIC HYDROXYQUINOLONES RECQL, DDX5, DHX35 KDM4E 1278/4885GLA 4146/4885CA12 4821/4885
US-10186668-B2 Organic electroluminescent material and use thereof EPB41, EPB41L2, MORF4L1 KDM4E 857/4885GLA 1197/4885CA12 3587/4885
US-20180254415-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND USE THEREOF EPB41, EPB41L2, MORF4L1 KDM4E 857/4885GLA 1197/4885CA12 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.