Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762392 | 0.84 | KDM4E (0.38) | KDM4EKMT2AGLAPOLBNOTUM | |
| SCHEMBL31030163 | 0.83 | KDM4E (0.42) | KDM4EKMT2APOLBNOTUMTDP1 | |
| SCHEMBL15713616 | 0.83 | KDM4E (0.42) | KDM4EKMT2AGLAPOLBTDP1 | |
| SCHEMBL6620704 | 0.83 | KDM4E (0.42) | KDM4EKMT2APOLBNOTUMTDP1 | |
| SCHEMBL11396178 | 0.79 | CD44 (0.43) | KDM4EKMT2AGLAPOLBNOTUM | |
| SCHEMBL5693090 | 0.79 | NOTUM (0.38) | NOTUMTDP1CYP3A4ACHEALKBH5 | |
| SCHEMBL28950924 | 0.78 | KDM4E (0.52) | KDM4EKMT2ANOTUMTDP1MAPT | |
| SCHEMBL18089697 | 0.78 | ALDH1A1 (0.44) | KDM4EKMT2ANOTUMTDP1MAPT | |
| SCHEMBL2953687 | 0.78 | CASP7 (0.44) | KDM4EKMT2AGLAPOLBTDP1 | |
| SCHEMBL19124930 | 0.78 | NOTUM (0.36) | NOTUMTDP1CYP3A4ACHEALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250100993-A1 | 2-SUBSTITUTED THIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2025-03-27 | — | — | US | disclosed |
| EP-4469451-A1 | 2-SUBSTITUTED THIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | Inipharm, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146897-A1 | 2-SUBSTITUTED THIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146897-A1 | 2-SUBSTITUTED THIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| US-20170362508-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250100993-A1 | 2-SUBSTITUTED THIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | HSD17B1, HSD17B3, HSD17B13 | KDM4E 3777/4885KMT2A 3549/4885GLA 2749/4885 |
| US-20170362508-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | PBDC1, RCC1, PUF60 | KDM4E 3572/4885KMT2A 3518/4885GLA 1244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.