Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 1.00 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | HSD11B1 | P28845 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 2/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 1.00 |
| ▸ | USP7 | Q93009 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 1/20 | 1.00 |
| ▸ | CTSD | P07339 | 1/20 | 1.00 |
| ▸ | PTPRF | P10586 | 1/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 1/20 | 1.00 |
| ▸ | CETP | P11597 | 1/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 1/20 | 1.00 |
| ▸ | CES1 | P23141 | 1/20 | 1.00 |
| ▸ | ACP1 | P24666 | 1/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ursolic Acid SCHEMBL9883367 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL17641055 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL12181611 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL17381604 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL13828060 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL23314191 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL15382984 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL17381767 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL21819718 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL18806320 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200207802-A1 | URSOLIC ACID MORPHOLINE AND DIETHANOLAMINE SALTS | EMMYON, INC. (US) | 2020-07-02 | — | — | US | disclosed |
| WO-2020030814-A1 | METHODS FOR DELAYING OCCURRENCE OF NEW-ONSET TYPE 2 DIABETES AND FOR SLOWING PROGRESSION OF AND TREATING TYPE 2 DIABETES | DALCOR PHARMA UK LTD., LEATHERHEAD, ZUG BRANCH (CH) | 2020-02-13 | — | — | WO | disclosed |
| WO-2019055280-A1 | URSOLIC ACID MORPHOLINE AND DIETHANOLAMINE SALTS | EMMYON, INC. (US) | 2019-03-21 | — | — | WO | disclosed |
| US-20170196890-A1 | TGR5 AGONIST COMPLEXES FOR TREATING DIABETES AND CANCER | CITY OF HOPE | 2017-07-13 | — | — | US | disclosed |
| US-20150272922-A1 | Compounds for Reducing Glucocorticoids, and Methods of Treatment Thereof | BIONICHE ANIMAL HEALTH USA, INC. | 2015-10-01 | — | — | US | disclosed |
| US-20150272922-A1 | Compounds for Reducing Glucocorticoids, and Methods of Treatment Thereof | BIONICHE ANIMAL HEALTH USA, INC. | 2015-10-01 | — | — | US | disclosed |
| WO-2015096771-A1 | 2-OXO-1,2-DIHYDROBENZO[CD]INDOLE-6-SULFONAMIDE COMPOUND AND COMPOSITION AND USE THEREOF | 中国科学院广州生物医药与健康研究院 | 2015-07-02 | — | — | WO | disclosed |
| WO-2014071506-A1 | COMPOUNDS FOR REDUCING GLUCOCORTICOIDS, AND METHODS OF TREATMENT THEREOF | BIONICHE LIFE SCIENCES INC. (CA) | 2014-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150272922-A1 | Compounds for Reducing Glucocorticoids, and Methods of Treatment Thereof | NR3C1, NR5A1, NR3C2 | PTPN1 855/4885SENP1 3562/4885POLB 2280/4885 |
| US-20170196890-A1 | TGR5 AGONIST COMPLEXES FOR TREATING DIABETES AND CANCER | GLP1R, GCGR, GPR119 | PTPN1 1960/4885SENP1 4700/4885POLB 4363/4885 |
| US-20200207802-A1 | URSOLIC ACID MORPHOLINE AND DIETHANOLAMINE SALTS | NR1H4, SLC10A1, CYP7B1 | PTPN1 3949/4885SENP1 3893/4885POLB 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.