Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 1.00 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | HSD11B1 | P28845 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 2/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 1.00 |
| ▸ | USP7 | Q93009 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 1/20 | 1.00 |
| ▸ | CTSD | P07339 | 1/20 | 1.00 |
| ▸ | PTPRF | P10586 | 1/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 1/20 | 1.00 |
| ▸ | CETP | P11597 | 1/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 1/20 | 1.00 |
| ▸ | CES1 | P23141 | 1/20 | 1.00 |
| ▸ | ACP1 | P24666 | 1/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ursolic Acid SCHEMBL15714065 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL17641055 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL12181611 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL17381604 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL13828060 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL23314191 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL15382984 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL17381767 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL21819718 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 | |
| Ursolic Acid SCHEMBL18806320 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBHSD11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372290-A1 | FORMULATIONS COMPRISING BOTANICAL EXTRACTS | APEX BIOTECH RES PTY LTD (AU) | 2023-11-23 | — | — | US | disclosed |
| US-20230372290-A1 | FORMULATIONS COMPRISING BOTANICAL EXTRACTS | APEX BIOTECH RES PTY LTD (AU) | 2023-11-23 | — | — | US | disclosed |
| US-20230348457-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL LTD (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230348457-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL LTD (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230295151-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20230295151-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-11685735-B2 | Pharmaceutical composition comprising berberine salts for the treatment of various diseases or disorders | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2023-06-27 | — | — | US | disclosed |
| US-11685735-B2 | Pharmaceutical composition comprising berberine salts for the treatment of various diseases or disorders | SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD. (CN) | 2023-06-27 | — | — | US | disclosed |
| US-11660306-B2 | Treatment of Rett syndrome | COLD SPRING HARBOR LABORATORY (US) | 2023-05-30 | — | — | US | disclosed |
| US-11660306-B2 | Treatment of Rett syndrome | COLD SPRING HARBOR LABORATORY (US) | 2023-05-30 | — | — | US | disclosed |
| US-20130274256-A1 | NOVEL INHIBITORS OF BACTERIAL BIOFILMS AND RELATED METHODS | SEQUOIA SCIENCES, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-8324264-B1 | Inhibitors of bacterial biofilms and related methods | SEQUOIA SCIENCES, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| WO-2012154554-A1 | FATTY ACID TRITERPENE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2012-11-15 | — | — | WO | disclosed |
| US-20120135094-A1 | OREGANO AND MINT ANTI-INFLAMMATORY COMPOSITIONS AND METHODS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-05-31 | — | — | US | disclosed |
| US-20100041753-A1 | INHIBITION OF BIOFILM FORMATION | SEQUOIA SCIENCE, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-7612045-B2 | Compounds, compositions and methods for controlling biofilms and bacterial infections | SEQUOIA SCIENCES, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090192327-A1 | METHODS AND COMPOSITIONS FOR INHIBITING BIOFILMS | SEQUOIA SCIENCES, INC. (US) | 2009-07-30 | — | — | US | disclosed |
| US-20090192327-A1 | METHODS AND COMPOSITIONS FOR INHIBITING BIOFILMS | SEQUOIA SCIENCES, INC. (US) | 2009-07-30 | — | — | US | disclosed |
| US-20080145322-A1 | Componds, Composition and Method for Controlling Biofolms and Bacterail Infections | SEQUOIA SCIENCES, INC. | 2008-06-19 | — | — | US | disclosed |
| US-20070014739-A1 | Compositions and methods for controlling biofilms and bacterial infections | SEQUOIA SCIENCES, INC. | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348457-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | PTPN1 3843/4885SENP1 2903/4885POLB 2698/4885 |
| US-20230372290-A1 | FORMULATIONS COMPRISING BOTANICAL EXTRACTS | CYP11B1, CYP11B2, ABCB11 | PTPN1 967/4885SENP1 517/4885POLB 2294/4885 |
| US-20080145322-A1 | Componds, Composition and Method for Controlling Biofolms and Bacterail Infections | CFD, SBDS, F2 | PTPN1 2771/4885SENP1 958/4885POLB 3771/4885 |
| US-11685735-B2 | Pharmaceutical composition comprising berberine salts for the treatment of various diseases or disorders | CPT1B, CYP27A1, GLS2 | PTPN1 3728/4885SENP1 3418/4885POLB 2519/4885 |
| US-11660306-B2 | Treatment of Rett syndrome | MECP2, BDNF, NTRK2 | PTPN1 4223/4885SENP1 1592/4885POLB 4059/4885 |
| US-20130274256-A1 | NOVEL INHIBITORS OF BACTERIAL BIOFILMS AND RELATED METHODS | BLVRB, MMP8, PGLS | PTPN1 1923/4885SENP1 838/4885POLB 725/4885 |
| US-20230295151-A1 | BERBERINE SALTS, URSODEOXYCHOLIC SALTS AND COMBINATIONS, METHODS OF PREPARATION AND APPLICATION THEREOF | CYP27A1, NR1H4, CYP7A1 | PTPN1 3843/4885SENP1 2903/4885POLB 2698/4885 |
| US-20090192327-A1 | METHODS AND COMPOSITIONS FOR INHIBITING BIOFILMS | MMP9, TIMP3, MMP8 | PTPN1 1009/4885SENP1 1272/4885POLB 2401/4885 |
| US-20070014739-A1 | Compositions and methods for controlling biofilms and bacterial infections | RHOA, ALOX5, BLVRB | PTPN1 1158/4885SENP1 547/4885POLB 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.