Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30473858 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP1A2KDM4ECYP3A4SLC6A3 | |
| SCHEMBL7759530 | 0.84 | ALDH1A1 (0.64) | ALDH1A1CYP1A2KDM4ECYP3A4SLC6A3 | |
| SCHEMBL639563 | 0.84 | ALDH1A1 (0.64) | ALDH1A1CYP1A2KDM4ECYP3A4SLC6A3 | |
| SCHEMBL30473857 | 0.83 | ALDH1A1 (0.54) | ALDH1A1CYP1A2KDM4ECYP3A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL27529639 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP1A2KDM4ECYP3A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4200885 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP1A2KDM4ECYP3A4SLC6A3 | |
| SCHEMBL438354 | 0.80 | CYP1A2 (0.47) | ALDH1A1CYP1A2KDM4ECYP3A4SLC6A3 | |
| SCHEMBL29942045 | 0.78 | HDAC4 (0.46) | ALDH1A1CYP1A2CYP3A4NPSR1CES2 | |
| SCHEMBL2815738 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP3A4SLC6A3SLC6A2 | |
| SCHEMBL20993622 | 0.77 | CYP1A2 (0.45) | ALDH1A1CYP1A2KDM4ECYP3A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251674-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BioCryst Pharmaceuticals, Inc. (US) | 2017-12-06 | — | — | EP | disclosed |
| US-20170267681-A1 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | MIDCAP FINANCIAL TRUST, AS AGENT | 2017-09-21 | — | — | US | disclosed |
| US-20150291596-A1 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BIOCRYST PHARMACEUTICALS, INC. | 2015-10-15 | — | — | US | disclosed |
| EP-2919785-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | Biocryst Pharmaceuticals, Inc. (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014078778-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BIOCRYST PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| US-20110195066-A1 | QUINOLINE INHIBITORS OF TYROSINE KINASE | AUSPEX PHARMACEUTICALS, INC. (US) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291596-A1 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | RNGTT, DUT, RNMT | ALDH1A1 2817/4885CYP1A2 3288/4885KDM4E 1365/4885 |
| US-20110195066-A1 | QUINOLINE INHIBITORS OF TYROSINE KINASE | ABL1, FLT3, BTK | ALDH1A1 3045/4885CYP1A2 1892/4885KDM4E 1010/4885 |
| US-20170267681-A1 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | RNGTT, DUT, RNMT | ALDH1A1 2817/4885CYP1A2 3288/4885KDM4E 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.