SCHEMBL15720180

SCHEMBL15720180

CC(C)(OC(C)(C)c1nc(Cl)nc(Cl)n1)c1nc(Cl)nc(Cl)n1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 1/20 0.31
PDE4A P27815 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1319210 0.75 ALDH1A1 (0.50) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
SCHEMBL10874600 0.69 ALDH1A1 (0.41) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
Lithium SCHEMBL30416555 0.69 ALDH1A1 (0.89) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
SCHEMBL21834206 0.69 HSD17B10 (0.43)
SCHEMBL7195373 0.65 ALDH1A1 (0.38) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
Ammonia Solution, Strong SCHEMBL10340047 0.65 ALDH1A1 (1.00) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
SCHEMBL18889428 0.65 ALDH1A1 (1.00) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
SCHEMBL20781 0.65
SCHEMBL1332087 0.65
SCHEMBL10665040 0.63 ALDH1A1 (0.42) ALDH1A1ALOX15TSHRLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150291597-A1 NOVEL ORALLY BIOAVAILABLE BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF USING SAME GALLEON PHARMACEUTICALS, INC. 2015-10-15 US disclosed
EP-2920155-A2 NOVEL ORALLY BIOAVAILABLE BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF USING SAME Galleon Pharmaceuticals, Inc. (US) 2015-09-23 EP disclosed
WO-2014078575-A2 NOVEL ORALLY BIOAVAILABLE BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF USING SAME GALLEON PHARMACEUTICALS, INC. (US) 2014-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291597-A1 NOVEL ORALLY BIOAVAILABLE BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF USING SAME MTNR1B, TNNC1, PER2 ALDH1A1 1629/4885ALOX15 524/4885TSHR 3506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.