SCHEMBL15720865

SCHEMBL15720865

CCCCCCCC(=O)NC(CCCCCC)C(=O)NC(CCCC)C(=O)NCCN

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NMT1 P30419 6/20 0.63
NMT2 O60551 5/20 0.63
TLR2 O60603 1/20 0.62
SIRT6 Q8N6T7 1/20 0.59
SIRT1 Q96EB6 1/20 0.59
SLC6A5 Q9Y345 1/20 0.54
NOD1 Q9Y239 2/20 0.51
LPAR3 Q9UBY5 3/20 0.51
GLP1R P43220 3/20 0.50
GRIA1 P42261 1/20 0.50
LPAR1 Q92633 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2339541 1.00 NMT1 (0.63) NMT1NMT2TLR2SIRT6SIRT1
SCHEMBL15720614 1.00 NMT1 (0.63) NMT1NMT2TLR2SIRT6SIRT1
SCHEMBL18202817 0.94 NMT2 (0.59) NMT1NMT2TLR2SIRT6SIRT1
SCHEMBL2339540 0.91 SIRT6 (0.64) NMT1NMT2TLR2SIRT6SIRT1
SCHEMBL2284037 0.91 SIRT6 (0.64) NMT1NMT2TLR2SIRT6SIRT1
SCHEMBL15720613 0.91 SIRT6 (0.64) NMT1NMT2TLR2SIRT6SIRT1
SCHEMBL22821586 0.91 NMT1 (0.69) NMT1NMT2TLR2SIRT6SIRT1
SCHEMBL15720863 0.91 SIRT6 (0.64) NMT1NMT2TLR2SIRT6SIRT1
SCHEMBL22821588 0.90 NMT1 (0.63) NMT1NMT2TLR2SIRT6SIRT1
SCHEMBL23519401 0.88 SIRT6 (0.76) NMT1NMT2TLR2SIRT6SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170143835-A1 SUBSTITUTED ANIONIC COMPOUNDS CONSISTING OF A BACKBONE MADE UP OF A DISCRETE NUMBER OF SACCHARIDE UNITS ADOCIA (FR) 2017-05-25 US disclosed
EP-2920200-A1 SUBSTITUTED ANIONIC COMPOUNDS CONSISTING OF A BACKBONE CONSISTING OF A DISCRETE NUMBER OF SACCHARIDE UNITS Adocia (FR) 2015-09-23 EP disclosed
WO-2014076422-A9 SUBSTITUTED ANIONIC COMPOUNDS CONSISTING OF A BACKBONE CONSISTING OF A DISCRETE NUMBER OF SACCHARIDE UNITS ADOCIA (FR) 2014-10-16 WO disclosed
US-20140187499-A1 SUBSTITUTED ANIONIC COMPOUNDS CONSISTING OF A BACKBONE MADE UP OF A DISCRETE NUMBER OF SACCHARIDE UNITS ADOCIA (FR) 2014-07-03 US disclosed
WO-2014076422-A1 SUBSTITUTED ANIONIC COMPOUNDS CONSISTING OF A BACKBONE CONSISTING OF A DISCRETE NUMBER OF SACCHARIDE UNITS ADOCIA (FR) 2014-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170143835-A1 SUBSTITUTED ANIONIC COMPOUNDS CONSISTING OF A BACKBONE MADE UP OF A DISCRETE NUMBER OF SACCHARIDE UNITS ALG8, FUT8, UGT8 NMT1 117/4885NMT2 202/4885TLR2 1883/4885
US-20140187499-A1 SUBSTITUTED ANIONIC COMPOUNDS CONSISTING OF A BACKBONE MADE UP OF A DISCRETE NUMBER OF SACCHARIDE UNITS FUT6, FUT5, FUT8 NMT1 46/4885NMT2 76/4885TLR2 1756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.