Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 8/20 | 0.42 |
| ▸ | MMP3 | P08254 | 8/20 | 0.42 |
| ▸ | MMP9 | P14780 | 8/20 | 0.42 |
| ▸ | MMP13 | P45452 | 8/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877725 | 0.78 | MMP2 (0.57) | MMP2MMP3MMP9MMP13GPR139 | |
| SCHEMBL877541 | 0.75 | MMP2 (0.53) | NPSR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL15733265 | 0.68 | NPSR1 (0.48) | NPSR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL877350 | 0.68 | MMP2 (0.43) | MMP2MMP3MMP9MMP13GPR139 | |
| SCHEMBL7229433 | 0.67 | MMP2 (0.62) | MMP2MMP3MMP9MMP13GPR139 | |
| SCHEMBL874804 | 0.67 | MMP2 (0.44) | MMP2MMP3MMP9MMP13GPR139 | |
| SCHEMBL875125 | 0.67 | MMP2 (0.44) | MMP2MMP3MMP9MMP13GPR139 | |
| SCHEMBL877491 | 0.67 | MMP2 (0.46) | NPSR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7229291 | 0.66 | MMP2 (0.81) | NPSR1MMP2MMP3MMP9MMP13 | |
| SCHEMBL15733014 | 0.65 | MMP2 (0.42) | MMP2MMP3MMP9MMP13GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148459-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148459-A1 | MATRIX METALLOPROTEINASE INHIBITORS | MMP9, MMP12, MMP10 | NPSR1 903/4885MMP2 17/4885MMP3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.