SCHEMBL15734993

SCHEMBL15734993

OC(O)(O[SiH3])c1ccc(-c2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.49
MAOB P27338 1/20 0.48
KDM1A O60341 1/20 0.47
AGXT P21549 1/20 0.44
SLC13A5 Q86YT5 1/20 0.44
PTPN1 P18031 2/20 0.43
CES2 O00748 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
PTPN5 P54829 1/20 0.41
PGR P06401 1/20 0.41
ASIC3 Q9UHC3 1/20 0.41
S1PR5 Q9H228 1/20 0.41
BACE1 P56817 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15733997 0.85 RXRA (0.50) KIF11CES2BACE1
SCHEMBL15735018 0.84 KIF11 (0.54) KIF11MAOBCES2CA1CA2
SCHEMBL15738537 0.83 CES2 (0.50) KIF11CES2TSHRMAPK1CA1
SCHEMBL15735449 0.82 TAAR1 (0.53) PTPN1MMP1MMP2MMP9MMP8
SCHEMBL15734494 0.81 MAOB (0.48) KIF11MAOBKDM1AAGXTPTPN5
SCHEMBL16068255 0.80 KIF11 (0.67) KIF11MAOBKDM1AAGXTPTPN1
SCHEMBL26827704 0.78 MAOB (0.62) KIF11MAOBKDM1AAGXTSLC13A5
SCHEMBL15733955 0.78 KIF11 (0.43) KIF11CES2TSHRPLAU
SCHEMBL15734712 0.77 MAOB (0.48) KIF11MAOBKDM1AAGXTSLC13A5
SCHEMBL24106776 0.77 KIF11 (0.67) KIF11MAOBKDM1ASLC13A5PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed