Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | F2RL1 | P55085 | 16/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697210 | 0.89 | NPC1 (0.42) | NPC1RAB9AF2RL1 | |
| SCHEMBL697214 | 0.87 | CES2 (0.41) | NPC1RAB9AF2RL1CES2CES1 | |
| SCHEMBL697323 | 0.79 | NPC1 (0.56) | NPC1RAB9AF2RL1CES2CES1 | |
| SCHEMBL696628 | 0.79 | NPC1 (0.47) | NPC1RAB9A | |
| SCHEMBL11137294 | 0.78 | NPC1 (0.42) | NPC1RAB9A | |
| SCHEMBL703290 | 0.74 | NPC1 (0.44) | NPC1RAB9AF2RL1 | |
| SCHEMBL697784 | 0.74 | MTOR (0.47) | NPC1RAB9A | |
| SCHEMBL1573433 | 0.74 | KMT2A (0.37) | NPC1RAB9AF2RL1CES2CES1 | |
| SCHEMBL712135 | 0.71 | NPC1 (0.65) | NPC1RAB9ACES2CES1 | |
| SCHEMBL697587 | 0.71 | KMT2A (0.42) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |