SCHEMBL15735643

SCHEMBL15735643

CC(=O)O[Si](OC(C)=O)(OC(C)=O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
NR4A1 P22736 1/20 0.43
NR4A2 P43354 1/20 0.43
NR4A3 Q92570 1/20 0.43
BACE1 P56817 1/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
EPHX2 P34913 1/20 0.41
MAOB P27338 1/20 0.41
CFTR P13569 1/20 0.40
SRD5A2 P31213 1/20 0.40
MAPT P10636 1/20 0.40
KIF11 P52732 1/20 0.40
GSK3B P49841 2/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15733924 0.95 KIF11 (0.47) CES2CES1NR4A1NR4A2NR4A3
SCHEMBL706708 0.85 HPGD (0.34) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL15736146 0.83 RXRA (0.53) CES2BACE1ALDH1A1KDM4EUSP2
SCHEMBL15736523 0.83 CES2 (0.44) CES2BACE1ALDH1A1KDM4EUSP2
SCHEMBL15735738 0.81 CES2 (0.46) CES2ALDH1A1KDM4EUSP2HPGD
SCHEMBL15734468 0.80 GAA (0.43) CES2CES1ALDH1A1KDM4EEPHX2
SCHEMBL15737056 0.80 CES2 (0.38) CES2CES1ALDH1A1MAOBMAPT
SCHEMBL15736402 0.80 KIF11 (0.51) BACE1ALDH1A1CYP2C19MAOBKIF11
SCHEMBL27722872 0.78 ESR1 (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL6562707 0.78 LMNA (0.48) CES2CES1ALDH1A1HPGDSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-107141313-A Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified 信越化学工业株式会社 2017-09-08 CN disclosed
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed