SCHEMBL15738726

SCHEMBL15738726

CCCCOC(=O)NCc1ccccc1C=O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.46
RAB9A P51151 4/20 0.46
NPC1 O15118 3/20 0.46
LMNA P02545 2/20 0.46
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
ACHE P22303 7/20 0.42
CTSK P43235 1/20 0.42
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 1/20 0.41
NFKB1 P19838 1/20 0.41
STAT1 P42224 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535968 0.86 SMN1; SMN2 (0.45) SMN1; SMN2RAB9ANPC1LMNATSHR
SCHEMBL11089043 0.82 HPGD (0.51) SMN1; SMN2RAB9ANPC1LMNATDP1
SCHEMBL7801637 0.81 ALDH1A1 (0.55) SMN1; SMN2RAB9ANPC1LMNATDP1
SCHEMBL3416627 0.81 RIPK1 (0.52) SMN1; SMN2RAB9ANPC1LMNATDP1
SCHEMBL6498349 0.80 TSHR (0.60) RAB9ANPC1TSHRHPGDHTT
SCHEMBL11472039 0.80 SMN1; SMN2 (0.50) SMN1; SMN2RAB9ANPC1LMNATDP1
SCHEMBL17773307 0.79 RAB9A (0.47) SMN1; SMN2RAB9ANPC1LMNATDP1
SCHEMBL28593323 0.78 NPC1 (0.58) SMN1; SMN2RAB9ANPC1LMNATSHR
SCHEMBL3806762 0.77 EPHX2 (0.56) SMN1; SMN2RAB9ANPC1LMNATDP1
SCHEMBL7799195 0.76 SMN1; SMN2 (0.51) SMN1; SMN2RAB9ANPC1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11092604-B2 Glucose sensor molecule BAXTER INTERNATIONAL INC. (US) 2021-08-17 US disclosed
EP-2663570-B1 GLUCOSE SENSOR MOLECULE LIGHTSHIP MEDICAL LTD (GB) 2018-07-18 EP disclosed
US-20160178638-A1 Glucose Sensor Molecule VANTIVE HEALTH GMBH (CH) 2016-06-23 US disclosed
US-9222941-B2 Glucose sensor molecules LIGHTSHIP MEDICAL LIMITED (GB) 2015-12-29 US disclosed
US-20140147934-A1 Glucose sensor molecules ARES CAPITAL CORPORATION 2014-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160178638-A1 Glucose Sensor Molecule GPR119, GCKR, IRS1 SMN1; SMN2 4315/4885RAB9A 2930/4885NPC1 2046/4885
US-20140147934-A1 Glucose sensor molecules GPR119, GCKR, IRS1 SMN1; SMN2 4311/4885RAB9A 2719/4885NPC1 1887/4885
US-11092604-B2 Glucose sensor molecule GPR119, GCKR, IRS1 SMN1; SMN2 4315/4885RAB9A 2930/4885NPC1 2046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.