Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077301 | 0.80 | ALDH1A1 (0.40) | RAB9AMAPTSMN1; SMN2NPC1FGFR1 | |
| SCHEMBL15020668 | 0.78 | GPR84 (0.41) | PTGS2CYP3A4KMT2A | |
| SCHEMBL3263731 | 0.78 | KDR (0.61) | L3MBTL1TDP1FGFR1KDR | |
| SCHEMBL14402704 | 0.75 | GRIN2B (0.48) | TDP1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL9228354 | 0.74 | GRIN2B (0.47) | TDP1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL2484621 | 0.74 | TLR8 (0.40) | PTGS2CYP3A4L3MBTL1TDP1RAB9A | |
| SCHEMBL1424104 | 0.74 | NOS3 (0.39) | PTGS2CYP3A4L3MBTL1TDP1RAB9A | |
| SCHEMBL28495876 | 0.74 | GRIN2B (0.47) | TDP1RAB9AMAPTKDM4EMEN1 | |
| SCHEMBL15886704 | 0.74 | L3MBTL1 (0.44) | PTGS2CYP3A4L3MBTL1TDP1RAB9A | |
| SCHEMBL9226687 | 0.73 | TLR8 (0.42) | PTGS2CYP3A4L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305274-A1 | Use of WNT stimulators for treating demyelinating diseases | Centre National de la Recherche Scientifique (CNRS) (FR) | 2011-04-06 | — | — | EP | disclosed |
| US-20080261821-A1 | Mechanism-Based Crosslinkers | THE REGENTS OF TE UNIVERSITY OF CALIFORNIA (US) | 2008-10-23 | — | — | US | disclosed |