Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16442471 | 0.81 | — | — | |
| SCHEMBL16396632 | 0.79 | ACHE (0.34) | — | |
| SCHEMBL21548743 | 0.77 | SKP2 (0.37) | NOS3NOS1NOS2MEN1NPC1 | |
| SCHEMBL32669352 | 0.76 | CA2 (0.32) | — | |
| SCHEMBL25972106 | 0.75 | CYP3A4 (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL28329297 | 0.75 | TRPA1 (0.43) | NPC1RAB9A | |
| SCHEMBL30046798 | 0.75 | CA1 (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL11045531 | 0.75 | MAPT (0.50) | NOS3NOS1NOS2MEN1NPC1 | |
| SCHEMBL32669229 | 0.72 | ALDH1A1 (0.53) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30699773 | 0.71 | ALDH1A1 (0.38) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470526-B1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2014-05-28 | — | — | EP | disclosed |