Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15744764 | 1.00 | APP (0.42) | APPGRM5CA12CA2CA9 | |
| SCHEMBL15744774 | 0.92 | WDR5 (0.38) | APPGRM5CA12CA2CA9 | |
| SCHEMBL2602434 | 0.87 | ACHE (0.48) | CA2CA9CA1WDR5ACHE | |
| SCHEMBL15744763 | 0.81 | ACHE (0.42) | CA2CA9CA1WDR5ACHE | |
| SCHEMBL25590575 | 0.77 | ENPP2 (0.44) | APPCA2CA1FFAR1 | |
| SCHEMBL14394344 | 0.76 | TEAD4 (0.56) | APPGRM5CA12CA2CA9 | |
| SCHEMBL9999906 | 0.76 | TEAD4 (0.56) | APPGRM5CA12CA2CA9 | |
| SCHEMBL9445826 | 0.75 | GRM5 (0.64) | APPGRM5CA12CA2CA9 | |
| SCHEMBL4457730 | 0.75 | GRM5 (0.64) | APPGRM5CA12CA2CA9 | |
| SCHEMBL14477632 | 0.75 | MEN1 (0.33) | CA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |