Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745659 | 0.94 | AR (0.30) | — | |
| SCHEMBL15764633 | 0.91 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL15745662 | 0.79 | AR (0.32) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL15745652 | 0.77 | AR (0.34) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL15745661 | 0.76 | ADRB2 (0.40) | — | |
| SCHEMBL15745658 | 0.76 | ADRB2 (0.39) | KDM4ELMNATSHR | |
| SCHEMBL15733061 | 0.75 | SMN1; SMN2 (0.45) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL15764632 | 0.75 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL15745646 | 0.75 | HSPA5 (0.38) | HTTPOLB | |
| SCHEMBL26328002 | 0.74 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9793483-B2 | Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |