SCHEMBL15745653

SCHEMBL15745653

CCCc1cc(Cc2cc(CCC)c(N)c(C(C)(O)C(F)(F)F)c2)cc(C(C)(O)C(F)(F)F)c1N

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.34
DHFR P00374 3/20 0.33
HSPA5 P11021 1/20 0.33
PGR P06401 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745654 0.92 TYR (0.33) HSPA5
SCHEMBL15745646 0.88 HSPA5 (0.38) ARDHFRHSPA5
SCHEMBL15764631 0.87 MEN1 (0.40) ARDHFRHSPA5PGRPTPN1
SCHEMBL15745662 0.80 AR (0.32) ARDHFR
SCHEMBL15745652 0.78 AR (0.34) ARDHFR
SCHEMBL15764648 0.78 MEN1 (0.38) PGR
SCHEMBL15745661 0.77 ADRB2 (0.40) ARPTPN1
SCHEMBL15745659 0.77 AR (0.30) AR
SCHEMBL15745658 0.77 ADRB2 (0.39) AR
SCHEMBL1100124 0.75 DHFR (0.41) DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-20140148571-A1 Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed