Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745846 | 0.89 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL7749694 | 0.84 | SMN1; SMN2 (0.82) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL18138255 | 0.84 | LMNA (0.67) | SMN1; SMN2LMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL3487087 | 0.83 | LMNA (0.61) | SMN1; SMN2LMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL137308 | 0.83 | LMNA (0.65) | SMN1; SMN2LMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL10876313 | 0.82 | ALDH1A1 (0.73) | SMN1; SMN2LMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL30229351 | 0.82 | SMN1; SMN2 (0.83) | SMN1; SMN2LMNAHTTL3MBTL1MAPT | |
| SCHEMBL733157 | 0.80 | LMNA (0.71) | SMN1; SMN2LMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL2918702 | 0.80 | GAA (0.64) | SMN1; SMN2LMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL3231538 | 0.79 | PPID (0.64) | SMN1; SMN2LMNAALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9222941-B2 | Glucose sensor molecules | LIGHTSHIP MEDICAL LIMITED (GB) | 2015-12-29 | — | — | US | disclosed |
| US-20140147934-A1 | Glucose sensor molecules | ARES CAPITAL CORPORATION | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140147934-A1 | Glucose sensor molecules | GPR119, GCKR, IRS1 | SMN1; SMN2 4311/4885LMNA 3142/4885ALDH1A1 2866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.