Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 3/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747846 | 0.97 | HPGDS (0.57) | HPGDSIDO1CYP11B1MAP4K4HSD17B1 | |
| SCHEMBL13917369 | 0.87 | HSD17B1 (0.48) | HPGDSIDO1MAP4K4HSD17B1HSD17B2 | |
| SCHEMBL1925054 | 0.83 | IDO1 (0.53) | IDO1HSD17B1HSD17B2MEN1MAPT | |
| SCHEMBL1926737 | 0.81 | IDO1 (0.51) | IDO1HSD17B1HSD17B2MEN1MAPT | |
| SCHEMBL27614819 | 0.81 | IDO1 (0.51) | IDO1HSD17B1HSD17B2MEN1MAPT | |
| SCHEMBL2482041 | 0.80 | HSD17B1 (0.47) | IDO1CYP11B1MAP4K4HSD17B1HSD17B2 | |
| SCHEMBL7392070 | 0.80 | HPGDS (0.58) | HPGDSIDO1CYP11B1MAP4K4HSD17B1 | |
| SCHEMBL6863681 | 0.79 | HPGDS (0.56) | HPGDSIDO1CYP11B1MAP4K4HSD17B1 | |
| SCHEMBL2318238 | 0.79 | HPGDS (0.60) | HPGDSIDO1CYP11B1MAP4K4HSD17B1 | |
| SCHEMBL15014085 | 0.79 | KDM1A (0.54) | IDO1HSD17B1HSD17B2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |