Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HK1 | P19367 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27614819 | 1.00 | IDO1 (0.51) | IDO1METAP2RAB9AALDH1A1MAPT | |
| SCHEMBL1925054 | 0.98 | IDO1 (0.53) | IDO1METAP2RAB9AALDH1A1MAPT | |
| SCHEMBL13917369 | 0.90 | HSD17B1 (0.48) | IDO1METAP2RAB9AALDH1A1MAPT | |
| SCHEMBL17027901 | 0.84 | IDO1 (0.58) | IDO1METAP2RAB9AALDH1A1MAPT | |
| SCHEMBL2482041 | 0.83 | HSD17B1 (0.47) | IDO1METAP2RAB9AALDH1A1GABRG2 | |
| SCHEMBL15747739 | 0.81 | HPGDS (0.56) | IDO1MAPTHSD17B1HSD17B2MEN1 | |
| SCHEMBL2482706 | 0.81 | CYP3A4 (0.54) | IDO1METAP2RAB9AALDH1A1MAPT | |
| SCHEMBL969090 | 0.81 | MAP4K4 (0.50) | METAP2RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL22660886 | 0.81 | HSD17B1 (0.54) | IDO1METAP2RAB9AALDH1A1MAPT | |
| SCHEMBL15014085 | 0.81 | KDM1A (0.54) | IDO1METAP2ALDH1A1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536333-B2 | Neutral metallic dendrimer complexes | ISIS INNOVATION LIMITED (GB) | 2013-09-17 | — | — | US | disclosed |
| US-20110127496-A1 | Neutral Metallic Dendrimer Complexes | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2011-06-02 | — | — | US | disclosed |
| US-7799917-B2 | Neutral metallic dendrimer complexes | ISIS INNOVATION LIMTED (GB) | 2010-09-21 | — | — | US | disclosed |
| EP-1532158-B1 | NEUTRAL METALLIC DENDRIMER COMPLEXES | ISIS INNOVATION (GB) | 2008-10-15 | — | — | EP | disclosed |
| US-20060119254-A1 | Neutral metallic dendrimer complexes | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060119254-A1 | Neutral metallic dendrimer complexes | ZYX, MLX, ZFX | IDO1 1602/4885METAP2 2375/4885RAB9A 1073/4885 |
| US-20110127496-A1 | Neutral Metallic Dendrimer Complexes | ZYX, MLX, ZFX | IDO1 1602/4885METAP2 2375/4885RAB9A 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.