Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13917369 | 0.92 | HSD17B1 (0.48) | HSD17B1HSD17B2NPC1RAB9ANFKB1 | |
| SCHEMBL12523554 | 0.86 | MAPK1 (0.56) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL1182292 | 0.86 | LDHA (0.52) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL1925054 | 0.85 | IDO1 (0.53) | HSD17B1HSD17B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29412558 | 0.84 | HSD17B1 (0.56) | HSD17B1HSD17B2NPC1RAB9ANFKB1 | |
| SCHEMBL30940583 | 0.84 | NPC1 (0.46) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL1926737 | 0.83 | IDO1 (0.51) | HSD17B1HSD17B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27614819 | 0.83 | IDO1 (0.51) | HSD17B1HSD17B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12957239 | 0.82 | HSD17B1 (0.67) | HSD17B1HSD17B2NPC1RAB9ANFKB1 | |
| SCHEMBL15747736 | 0.81 | NPC1 (0.53) | HSD17B1HSD17B2NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-3855519-A2 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | Universal Display Corporation (US) | 2021-07-28 | — | — | EP | disclosed |
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3428986-B1 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | UNIVERSAL DISPLAY CORP (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| EP-3428986-A1 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | Universal Display Corporation (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-1763902-B1 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | UNIVERSAL DISPLAY CORP (US) | 2018-08-29 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
| US-8603645-B2 | Stable and efficient electroluminescent materials | UNIVERSAL DISPLAY CORPORATION (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2378582-A1 | Stable and efficient electroluminescent materials | Universal Display Corporation (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20110060143-A1 | Stable and Efficient Electroluminescent Materials | KWONG RAYMOND | 2011-03-10 | — | — | US | disclosed |
| US-7851072-B2 | Stable and efficient electroluminescent materials | UNIVERSAL DISPLAY CORPORATION (US) | 2010-12-14 | — | — | US | disclosed |
| CN-101076902-B | Stable and effective electroluminescent material | UNIVERSAL DISPLAY CORP | 2010-07-28 | — | — | CN | disclosed |
| CN-101076902-A | Stable and effective electroluminescent material | UNIVERSAL DISPLAY CORP (US) | 2007-11-21 | — | — | CN | disclosed |
| EP-1763902-A2 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | Universal Display Corporation (US) | 2007-03-21 | — | — | EP | disclosed |
| US-20070003789-A1 | Stable and efficient electroluminescent materials | UNIVERSAL DISPLAY CORPORAITON | 2007-01-04 | — | — | US | disclosed |
| WO-2006014599-A2 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | HSD17B1 4860/4885HSD17B2 4834/4885NPC1 4039/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | HSD17B1 4527/4885HSD17B2 4245/4885NPC1 2761/4885 |
| US-20110060143-A1 | Stable and Efficient Electroluminescent Materials | EML4, ITGA5, CHRM5 | HSD17B1 4254/4885HSD17B2 3936/4885NPC1 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.