Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.74 |
| ▸ | NPC1 | O15118 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.64 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | USP7 | Q93009 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477302 | 0.94 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2920549 | 0.87 | NPC1 (0.69) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2979351 | 0.85 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2916169 | 0.85 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL517452 | 0.85 | NPC1 (0.73) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3633642 | 0.84 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL517808 | 0.84 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL518043 | 0.83 | NPC1 (0.74) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL517178 | 0.83 | NPC1 (0.74) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29927547 | 0.83 | NPC1 (0.74) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2739608-B1 | INSULIN SECRETION PROMOTING AGENTS | VAL-CHUM LTD PARTNERSHIP (CA) | 2017-09-06 | — | — | EP | disclosed |
| US-9518016-B2 | Insulin secretion promoting agents | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2016-12-13 | — | — | US | disclosed |
| US-9518016-B2 | Insulin secretion promoting agents | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2016-12-13 | — | — | US | disclosed |
| US-9518016-B2 | Insulin secretion promoting agents | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2016-12-13 | — | — | US | disclosed |
| US-20160264527-A1 | INSULIN SECRETION PROMOTING AGENTS | CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL (CA) | 2016-09-15 | — | — | US | disclosed |
| US-20160264527-A1 | INSULIN SECRETION PROMOTING AGENTS | CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL (CA) | 2016-09-15 | — | — | US | disclosed |
| US-20160264527-A1 | INSULIN SECRETION PROMOTING AGENTS | CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL (CA) | 2016-09-15 | — | — | US | disclosed |
| US-9371285-B2 | Insulin secretion promoting agents | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2016-06-21 | — | — | US | disclosed |
| US-9371285-B2 | Insulin secretion promoting agents | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2016-06-21 | — | — | US | disclosed |
| US-9371285-B2 | Insulin secretion promoting agents | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2016-06-21 | — | — | US | disclosed |
| WO-2015127559-A1 | ABHD6 ANTAGONISTS FOR PROMOTING BROWNING OF WHITE ADIPOSE TISSUE AND BROWN ADIPOSE TISSUE FUNCTIONALITY | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2015-09-03 | — | — | WO | disclosed |
| US-20140163077-A1 | INSULIN SECRETION PROMOTING AGENTS | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2014-06-12 | — | — | US | disclosed |
| US-20140163077-A1 | INSULIN SECRETION PROMOTING AGENTS | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2014-06-12 | — | — | US | disclosed |
| US-20140163077-A1 | INSULIN SECRETION PROMOTING AGENTS | VAL-CHUM, LIMITED PARTNERSHIP (CA) | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264527-A1 | INSULIN SECRETION PROMOTING AGENTS | IAPP, GPR119, PNLIP | RAB9A 2214/4885NPC1 600/4885SMN1; SMN2 2343/4885 |
| US-20140163077-A1 | INSULIN SECRETION PROMOTING AGENTS | IAPP, GPR119, PNLIP | RAB9A 2214/4885NPC1 600/4885SMN1; SMN2 2343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.