SCHEMBL157695

SCHEMBL157695

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nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PMP22 Q01453 2/20 0.59
GSR P00390 2/20 0.52
GRM8 O00222 1/20 0.52
GRM6 O15303 1/20 0.52
GRIN2D O15399 1/20 0.52
GRIN3B O60391 1/20 0.52
CYP1A2 P05177 1/20 0.52
GRIK1 P39086 1/20 0.52
GRM5 P41594 1/20 0.52
GRIA1 P42261 1/20 0.52
GRIA2 P42262 1/20 0.52
GRIA3 P42263 1/20 0.52
SLC1A3 P43003 1/20 0.52
SLC1A2 P43004 1/20 0.52
SLC1A1 P43005 1/20 0.52
GRIA4 P48058 1/20 0.52
GRIN1 Q05586 1/20 0.52
GRIN2A Q12879 1/20 0.52
GRIK2 Q13002 1/20 0.52
GRIK3 Q13003 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193067 1.00 PMP22 (0.59) PMP22GSRGRM8GRM6GRIN2D
SCHEMBL157694 1.00 PMP22 (0.59) PMP22GSRGRM8GRM6GRIN2D
Bromide SCHEMBL8445234 0.98 PMP22 (0.57) PMP22GSRGRM8GRM6GRIN2D
Hydrochloric Acid SCHEMBL26699118 0.98 PMP22 (0.57) PMP22GSRGRM8GRM6GRIN2D
SCHEMBL28766377 0.98 PMP22 (0.57) PMP22GSRGRM8GRM6GRIN2D
Hydrochloric Acid SCHEMBL26699117 0.98 PMP22 (0.57) PMP22GSRGRM8GRM6GRIN2D
Bromide SCHEMBL8445230 0.98 PMP22 (0.57) PMP22GSRGRM8GRM6GRIN2D
Homocysteine SCHEMBL27998293 0.89 PMP22 (0.50) PMP22GSRGRM8GRM6GRIN2D
SCHEMBL38660644 0.89 GSR (0.54) PMP22GSRGRM8GRM6GRIN2D
Lysine SCHEMBL1080025 0.86 GSR (0.74) PMP22GSRCYP1A2BLMARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1770 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103499-A1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS HAN JIE (US) 2026-04-16 US claimed
EP-3986363-B1 FORMULATIONS FOR ODONTOLOGICAL AND DERMATOLOGICAL USE CONTAINING TRICHLOROACETATE SALTS AND HYDROXYACIDS WIQO S P A (IT) 2025-12-03 EP claimed
EP-3956355-B1 STABILIZATION OF PRANDIAL OR BASAL INSULIN ANALOGUES BY AN INTERNAL DISELENIDE BRIDGE UNIV INDIANA TRUSTEES (US) 2025-11-26 EP claimed
EP-3448417-B1 INSULIN DIMER-INCRETIN CONJUGATES MERCK SHARP & DOHME LLC (US) 2025-11-12 EP claimed
US-12419551-B2 Mediation of in vivo analyte signal degradation SENSEONICS, INCORPORATED (US) 2025-09-23 US claimed
EP-3880688-B1 OLIGOSACCHARIDE PREPARATIONS AND COMPOSITIONS DSM IP ASSETS BV (NL) 2025-09-17 EP claimed
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO claimed
WO-2025065271-A1 METHODS AND DEVICES FOR TREATING DEPRESSION Liangzhu Laboratory (CN) 2025-04-03 WO claimed
EP-3965657-B1 MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION SENSEONICS INC (US) 2025-03-05 EP claimed
US-20250051416-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2025-02-13 US claimed
EP-0336387-A2 Process for producing L-arginine KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1989-10-11 EP claimed
US-4412943-A CONTAINING AN ALKYLENEDIAMINE CARBOXYLIC ACID DERIVATIVE AND AN AMMONIUM SULFATE KAO SOAP CO., LTD. (JP) 1983-11-01 US claimed
US-4302593-A RECOVERING THE AMINO ACID FROM THE COMPOUND AS A MEANS OF SEPARATION OR PURIFICATION FROM SOLUTION LOWE ORVILLE G 1981-11-24 US claimed
US-4283386-A APPLYING A CYSTEIC ACID COMPOUND AND A METALLIC COMPOUND SCOTT EUGENE J VAN 1981-08-11 US claimed
US-4273684-A Transparent detergent bar AJINOMOTO CO., INC. (JP) 1981-06-16 US claimed
US-4246261-A HYDROXY ACIDS, ESTERS, LACTONES SCOTT EUGENE J VAN 1981-01-20 US claimed
US-4228304-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIULCER AGENTS, BACTERICIDES, ANTITHROMBOTIC AGENTS AND FOR LIVER DISORDERS, OR AS SURFACTANTS IN DETERGENTS AND OIL ADDITIVES HISAMITSU PHARMACEUTICAL CO. INC. (JP) 1980-10-14 US claimed
US-4224339-A Treatment of disturbed keratinization SCOTT EUGENE J VAN 1980-09-23 US claimed
US-4053630-A FOR ACNE, DANDRUFF AND ICTHYOTIC SKIN CONDITIONS; CYSTEIC, HOMOCYSTEIC, CYSTEINESULFINIC ACID OR METAL CHELATES THEREOF YU RUEY J 1977-10-11 US claimed
US-3985722-A Process for preparing N-higher aliphatic acyl derivatives of amino acids, peptides or proteins AJINOMOTO CO., INC. (JA) 1976-10-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12419551-B2 Mediation of in vivo analyte signal degradation SLC2A1, TXN2, SLC2A8 PMP22 3284/4885GSR 41/4885GRM8 615/4885
US-20260103499-A1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS CBR1, CBR3, SIGMAR1 PMP22 2621/4885GSR 143/4885GRM8 2965/4885
US-20250051416-A1 INSULIN RECEPTOR PARTIAL AGONISTS INSR, GPR119, IRS1 PMP22 4457/4885GSR 1243/4885GRM8 407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.