Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775298 | 0.87 | ALDH1A1 (0.38) | SMN1; SMN2TYRMAOBSRD5A1ALDH1A1 | |
| SCHEMBL15775290 | 0.86 | RAB9A (0.38) | PDE3BPDE3ASMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL15775479 | 0.86 | NOTUM (0.39) | TYRMAOBGAA | |
| SCHEMBL15775423 | 0.83 | PDCD1 (0.38) | CHRM5PDE3BPDE3AMAOB | |
| SCHEMBL15775414 | 0.83 | SMN1; SMN2 (0.38) | PTPRCSMN1; SMN2TYRMAOBALDH1A1 | |
| SCHEMBL15775756 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL4774575 | 0.76 | MAOA (0.40) | PTPRCSMN1; SMN2MAOBALDH1A1TSHR | |
| Bromide SCHEMBL15775833 | 0.73 | RXFP1 (0.34) | PDE3BPDE3ASMN1; SMN2TYRMAOB | |
| SCHEMBL15775398 | 0.71 | RAB9A (0.40) | SMN1; SMN2TYRALDH1A1TSHRADORA3 | |
| SCHEMBL15775915 | 0.70 | MAPT (0.40) | PTPRCSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |