Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775583 | 0.88 | TDP1 (0.49) | KMT2AMAPTRECQLMCL1RXFP1 | |
| SCHEMBL15775915 | 0.87 | MAPT (0.40) | KMT2AMAPTRECQLMCL1RXFP1 | |
| SCHEMBL15775327 | 0.84 | KMT2A (0.38) | KMT2AMAPTRECQLMCL1RXFP1 | |
| SCHEMBL15775318 | 0.84 | HTR7 (0.42) | KMT2AMAPTRECQLMCL1RXFP1 | |
| SCHEMBL15776267 | 0.79 | NOTUM (0.39) | KMT2AMAPTMEN1ALDH1A1NOTUM | |
| SCHEMBL15775479 | 0.79 | NOTUM (0.39) | RXFP1NOTUMHTTNPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL15775431 | 0.77 | NOTUM (0.38) | KMT2AMAPTRXFP1MEN1NOTUM | |
| SCHEMBL15776282 | 0.75 | CYP19A1 (0.41) | RXFP1ALDH1A1NOTUM | |
| SCHEMBL15775233 | 0.72 | MAPT (0.43) | KMT2AMAPTRECQLMCL1RXFP1 | |
| SCHEMBL1721464 | 0.69 | ALDH1A1 (0.71) | KMT2AMAPTS100A4MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |