Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KLK3 | P07288 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775768 | 0.88 | KMT2A (0.40) | TDP1ALDH1A1KMT2AMAPTRECQL | |
| SCHEMBL15775915 | 0.88 | MAPT (0.40) | TDP1ALDH1A1KMT2AMAPTRECQL | |
| SCHEMBL15775327 | 0.85 | KMT2A (0.38) | TDP1ALDH1A1KMT2AMAPTRECQL | |
| SCHEMBL15775318 | 0.85 | HTR7 (0.42) | TDP1ALDH1A1KMT2AMAPTRECQL | |
| SCHEMBL15775665 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MAPTGAAPTPRCSMN1; SMN2 | |
| SCHEMBL15775298 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL15775397 | 0.77 | ACHE (0.40) | TDP1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL15775233 | 0.75 | MAPT (0.43) | TDP1ALDH1A1KMT2AMAPTRECQL | |
| SCHEMBL15775467 | 0.74 | ALDH1A1 (0.36) | ALDH1A1MAPTRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL15775346 | 0.73 | ACHE (0.43) | ALDH1A1MAPTGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |