Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775198 | 0.86 | MAPT (0.39) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL15775349 | 0.77 | PARP1 (0.37) | MAPTRECQLKMT2APTPRCALDH1A1 | |
| SCHEMBL15775583 | 0.75 | TDP1 (0.49) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL15775915 | 0.72 | MAPT (0.40) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL15775768 | 0.72 | KMT2A (0.40) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL15775318 | 0.72 | HTR7 (0.42) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL8499259 | 0.72 | MAPT (0.66) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL331390 | 0.72 | S100A4 (0.46) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL15775327 | 0.69 | KMT2A (0.38) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL9194546 | 0.69 | S100A4 (0.46) | MAPTRECQLKMT2AMCL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |