Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899970 | 0.92 | LMNA (0.35) | CNR1MEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL1814508 | 0.80 | MEN1 (0.42) | MEN1KMT2ALMNACHRNB2SLC6A2 | |
| SCHEMBL7734302 | 0.75 | LMNA (0.34) | KMT2AHCRTR1HCRTR2LMNAMAPT | |
| SCHEMBL1817756 | 0.75 | KMT2A (0.40) | KMT2AHCRTR1HCRTR2LMNAMAPT | |
| SCHEMBL1818873 | 0.71 | MAPK1 (0.41) | MEN1KMT2ALMNACHRNB2SLC6A2 | |
| SCHEMBL15799984 | 0.71 | CHRNB2 (0.39) | MEN1KMT2ALMNACHRNB2SLC6A2 | |
| SCHEMBL1817884 | 0.65 | MAPK1 (0.56) | KMT2ALMNACHRNB2SLC6A2CHRNB4 | |
| SCHEMBL21319702 | 0.65 | KMT2A (0.37) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL15373204 | 0.64 | MAPK1 (0.52) | RAB9ANPC1MEN1KMT2AHCRTR1 | |
| SCHEMBL7270762 | 0.62 | ALDH1A1 (0.50) | RAB9ANPC1PKMCNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754207-B2 | Process for the preparation of rapamycin derivatives | CADILA HEALTHCARE LIMITED (IN) | 2014-06-17 | — | — | US | disclosed |