Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.49 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.49 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.49 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.49 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.49 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16874836 | 0.96 | OPRM1 (0.59) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL16874714 | 0.90 | HSD11B1 (0.56) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL1581964 | 0.85 | KMT2A (0.52) | SMN1; SMN2KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL8161638 | 0.84 | USP2 (0.67) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL1581749 | 0.84 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL8319710 | 0.84 | SMN1; SMN2 (0.57) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL1581921 | 0.81 | KDM4E (0.50) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL1581427 | 0.81 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL1581499 | 0.81 | MEN1 (0.58) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL16874757 | 0.80 | OPRM1 (0.48) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720872-B1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2011-04-20 | — | — | EP | disclosed |