SCHEMBL158167

SCHEMBL158167

Nc1c(C(=O)O)cccc1C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.55
CASP7 P55210 1/20 0.55
CASP6 P55212 1/20 0.55
TAS2R14 Q9NYV8 5/20 0.50
FABP4 P15090 1/20 0.49
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
MMP2 P08253 1/20 0.46
ALDH1A1 P00352 3/20 0.45
PTGS1 P23219 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 1/20 0.44
DHODH Q02127 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
CFTR P13569 1/20 0.43
UCHL1 P09936 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11631331 0.98 G6PD (0.53) G6PDCASP7CASP6TAS2R14FABP4
SCHEMBL28337787 0.89 G6PD (0.45) G6PDCASP7CASP6TAS2R14FABP4
SCHEMBL160696 0.85 PARP1 (0.47) TAS2R14FABP4LMNAGAAALDH1A1
SCHEMBL29442193 0.85 PARP1 (0.47) TAS2R14FABP4LMNAGAAALDH1A1
SCHEMBL1358529 0.84 ALDH1A1 (0.49) G6PDCASP7CASP6TAS2R14FABP4
SCHEMBL4865222 0.84 UCHL1 (0.50) G6PDCASP7CASP6TAS2R14FABP4
SCHEMBL28337788 0.84 TAS2R14 (0.42) G6PDCASP7CASP6TAS2R14FABP4
SCHEMBL11853497 0.83 PTGS1 (0.48) TAS2R14FABP4LMNAGAAPTGS1
SCHEMBL11631326 0.83 LMNA (0.44) G6PDCASP7CASP6TAS2R14FABP4
SCHEMBL1124058 0.82 MAPT (0.53) LMNAGAAALDH1A1PTGS1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119531139-A Wear-resistant and soil-release case fabric and processing method thereof 南通友途新材料科技有限公司 2025-02-28 CN claimed
CN-115448835-A Synthetic method of 2-fluoro-3- (trifluoromethyl) benzoic acid 苏州莱克施德药业有限公司 2022-12-09 CN claimed
WO-2016071485-A1 METHOD FOR DETERMINING THE COMPOSITION OF THE SUGAR MOIETY OF A SUGAR CONTAINING COMPOUND DANMARKS TEKNISKE UNIVERSITET (DK) 2016-05-12 WO claimed
US-9040268-B2 Method for controlling undesirable byproducts formation caused by contaminating organisms in the production of ethanol from syngas COSKATA, INC. (US) 2015-05-26 US claimed
EP-2758540-A1 METHOD FOR CONTROLLING UNDESIRABLE BYPRODUCTS FORMATION CAUSED BY CONTAMINATING ORGANISMS IN THE PRODUCTION OF ETHANOL FROM SYNGAS Coskata Energy Inc. (US) 2014-07-30 EP claimed
CN-103958690-A Method for controlling undesirable byproducts formation caused by contaminating organisms in the production of ethanol from syngas COSKATA INC 2014-07-30 CN claimed
WO-2013043513-A1 METHOD FOR CONTROLLING UNDESIRABLE BYPRODUCTS FORMATION CAUSED BY CONTAMINATING ORGANISMS IN THE PRODUCTION OF ETHANOL FROM SYNGAS COSKATA, INC. (US) 2013-03-28 WO claimed
US-20130071897-A1 METHOD FOR CONTROLLING UNDESIRABLE BYPRODUCTS FORMATION CAUSED BY CONTAMINATING ORGANISMS IN THE PRODUCTION OF ETHANOL FROM SYNGAS COSKATA, INC. (US) 2013-03-21 US claimed
US-20260008791-A1 CHEMICAL COMPOUNDS BORAH INC (US) 2026-01-08 US disclosed
US-20260008770-A1 CBL-B INHIBITORS AND METHODS OF USES THEREOF INSILICO MEDICINE IP LTD (HK) 2026-01-08 US disclosed
US-12404270-B2 Quinazoline derivatives as LPA receptor 2 inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2025-09-02 US disclosed
US-12358932-B2 Chemical compounds BORAH, INC. (US) 2025-07-15 US disclosed
WO-2025137293-A2 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS Roche Sequencing Solutions, Inc. (US) 2025-06-26 WO disclosed
EP-4558504-A1 CBL-B INHIBITORS AND METHODS OF USES THEREOF Insilico Medicine IP Limited (HK) 2025-05-28 EP disclosed
US-4440941-A Aroyl-aminoacids, amides and esters thereof USV PHARMACEUTICAL CORPORATION (US) 1984-04-03 US disclosed
US-4397856-A Analgesic 4-hydroxy-3-quinolinecarboxamides ROUSSEL UCLAF (FR) 1983-08-09 US disclosed
EP-0054936-A1 Aroyl amino acids USV PHARMACEUTICAL CORPORATION (US) 1982-06-30 EP disclosed
US-4307113-A TREATMENT OF DIABETES SANDOZ, INC. (US) 1981-12-22 US disclosed
US-4107310-A ANALGESICS ROUSSEL UCLAF (FR) 1978-08-15 US disclosed
US-4060638-A TRANQUILIZER, MUSCLE RELAXANT SANDOZ, INC. (US) 1977-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008791-A1 CHEMICAL COMPOUNDS JAK3, JAK2, JAK1 G6PD 1993/4885CASP7 1285/4885CASP6 665/4885
US-20260008770-A1 CBL-B INHIBITORS AND METHODS OF USES THEREOF CBL, CBLC, CBLB G6PD 2757/4885CASP7 4117/4885CASP6 2705/4885
US-12404270-B2 Quinazoline derivatives as LPA receptor 2 inhibitors LPAR2, LPAR1, LPAR5 G6PD 4151/4885CASP7 3736/4885CASP6 4643/4885
US-12358932-B2 Chemical compounds PDE4A, PDE4B, SYK G6PD 1669/4885CASP7 1793/4885CASP6 1126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.