Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 4/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832363 | 0.80 | ALDH1A1 (0.44) | ALDH1A1OPRM1LMNAOPRK1PTBP1 | |
| SCHEMBL1613958 | 0.75 | L3MBTL1 (0.34) | ALDH1A1LMNAPTBP1UBE2MDCUN1D1 | |
| SCHEMBL16372187 | 0.73 | OPRL1 (0.34) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1932588 | 0.73 | L3MBTL1 (0.41) | ALDH1A1LMNAPTBP1UBE2MDCUN1D1 | |
| SCHEMBL3829259 | 0.72 | OPRM1 (0.44) | ALDH1A1OPRM1LMNAPTBP1UBE2M | |
| SCHEMBL5510945 | 0.71 | L3MBTL1 (0.42) | L3MBTL1 | |
| SCHEMBL2144953 | 0.70 | L3MBTL1 (0.37) | ALDH1A1LMNAPTBP1L3MBTL1 | |
| SCHEMBL3818321 | 0.70 | SLC6A4 (0.44) | L3MBTL1 | |
| SCHEMBL2371705 | 0.69 | L3MBTL1 (0.44) | ALDH1A1OPRM1LMNAPTBP1L3MBTL1 | |
| SCHEMBL16055381 | 0.68 | SLC6A4 (0.40) | OPRM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935260-A1 | BET-PROTEIN-INHIBITING DIHYDROPYRIDOPYRAZINONES | Bayer Pharma Aktiengesellschaft (DE) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095774-A1 | BET-PROTEIN-INHIBITING DIHYDROPYRIDOPYRAZINONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-06-26 | — | — | WO | disclosed |