Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 8/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832363 | 0.80 | ALDH1A1 (0.44) | OPRM1KMT2AUBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL5510945 | 0.80 | L3MBTL1 (0.42) | KMT2A | |
| SCHEMBL1932588 | 0.78 | L3MBTL1 (0.41) | UBE2MDCUN1D1ALDH1A1LMNAPTBP1 | |
| SCHEMBL3818321 | 0.78 | SLC6A4 (0.44) | — | |
| SCHEMBL5027243 | 0.75 | L3MBTL1 (0.39) | UBE2MDCUN1D1ALDH1A1LMNAPTBP1 | |
| SCHEMBL2371705 | 0.74 | L3MBTL1 (0.44) | OPRM1SMN1; SMN2ALDH1A1LMNAPTBP1 | |
| SCHEMBL6631588 | 0.74 | OPRM1 (0.39) | OPRM1ALDH1A1LMNAPTBP1 | |
| SCHEMBL2053926 | 0.74 | SMN1; SMN2 (0.48) | OPRM1SMN1; SMN2 | |
| SCHEMBL25566050 | 0.74 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2 | |
| SCHEMBL5484262 | 0.73 | NAAA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |