Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10978004 | 0.77 | TGM2 (0.46) | TDP1CA9TGM2CA12HSD17B10 | |
| SCHEMBL8516545 | 0.71 | TDP1 (0.44) | TDP1CA9TGM2CA12ALDH1A1 | |
| SCHEMBL4892692 | 0.71 | TDP1 (0.44) | TDP1CA9TGM2CA12ALDH1A1 | |
| SCHEMBL27337982 | 0.71 | TDP1 (0.56) | TDP1CA9TGM2CA12ALDH1A1 | |
| SCHEMBL3337536 | 0.71 | TDP1 (0.44) | TDP1CA9TGM2CA12ALDH1A1 | |
| SCHEMBL646260 | 0.71 | TDP1 (0.44) | TDP1CA9TGM2CA12ALDH1A1 | |
| SCHEMBL4964227 | 0.71 | TDP1 (0.44) | TDP1CA9TGM2CA12ALDH1A1 | |
| SCHEMBL2350755 | 0.71 | TDP1 (0.56) | TDP1CA9TGM2CA12ALDH1A1 | |
| SCHEMBL2786299 | 0.71 | TDP1 (0.44) | TDP1CA9TGM2CA12ALDH1A1 | |
| SCHEMBL5539582 | 0.71 | TGM2 (0.47) | TDP1CA9TGM2CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945702-A1 | HYDROXY ALIPHATIC SUBSTITUTED PHENYL AMINOALKYL ETHER DERIVATIVES | Prous Institute for Biomedical Research, S.A. (ES) | 2015-11-25 | — | — | EP | disclosed |
| WO-2014096377-A1 | HYDROXY ALIPHATIC SUBSTITUTED PHENYL AMINOALKYL ETHER DERIVATIVES | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2014-06-26 | — | — | WO | disclosed |