Sugi Predict

Sugi Predict / Compounds / SCHEMBL3337536

SCHEMBL3337536

SCHEMBL3337536

C=CC(F)Nc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.44
▸ ALDH1A1 P00352 7/20 0.39
▸ TSHR P16473 5/20 0.39
▸ HSD17B10 Q99714 4/20 0.39
▸ ALOX15 P16050 3/20 0.39
▸ ALOX12 P18054 3/20 0.39
▸ CYP3A4 P08684 3/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ THRB P10828 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ ATM Q13315 1/20 0.39
▸ CA12 O43570 1/20 0.38
▸ CA9 Q16790 1/20 0.38
▸ TGM2 P21980 1/20 0.38
▸ CTSD P07339 1/20 0.36
▸ MAPK1 P28482 2/20 0.35
▸ PTGS2 P35354 2/20 0.35
▸ PTGS1 P23219 1/20 0.35
▸ SLC6A2 P23975 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2786299 0.73 TDP1 (0.44) TDP1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL27337982 0.73 TDP1 (0.56) TDP1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL2350755 0.73 TDP1 (0.56) TDP1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL4964227 0.73 TDP1 (0.44) TDP1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL646260 0.73 TDP1 (0.44) TDP1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL8516545 0.73 TDP1 (0.44) TDP1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL4892692 0.73 TDP1 (0.44) TDP1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL2020475 0.72 TDP1 (0.55) TDP1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL5440741 0.71 TDP1 (0.43) TDP1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL15826348 0.71 TDP1 (0.43) TDP1ALDH1A1TSHRHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115559119-B Multifunctional super-hydrophobic fabric and preparation method thereof 苏州大学 2024-07-05 — — CN claimed
WO-2016183101-A1 PALLADIUM-CATALYZED ARYLATION OF FLUOROALKYLAMINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-11-17 — — WO claimed
EP-2134170-B1 FLUORALKYLPHENYLAMIDINES AND THEIR USE AS FUNGICIDES BAYER IP GMBH (DE) 2015-06-03 — — EP claimed
US-20100093534-A1 FLUORALKYLPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-04-15 — — US claimed
EP-1110939-B1 Process for the preparation of poly(fluoroalkyl)-acetophenones BAYER AG (DE) 2003-09-10 — — EP claimed
US-6410796-B2 PREPARING A DIAZONIUM SALT MIXTURE FROM THE FLUOROALKYL ANILINE COMPOUND, REACTING DIAZONIUM SALT MIXTURE WITH ACETALDOXIME IN PRESENCE OF HALIDE IONS, ATLEAST OTHER STRONG ACID, AND A COPPER AND/OR PALLADIUM COMPOUND, FREE OF BUFFER BAYER AKTIENGESELLSCHAFT (DE) 2002-06-25 — — US claimed
EP-0983223-B1 METHOD FOR PREPARING ACETOPHENONES WITH A FLUORALKYL-SUBSTITUTED AROMATIC NUCLEUS BAYER AG (DE) 2002-03-06 — — EP claimed
US-20010005767-A1 Process for the preparation of poly(fluoroalkyl)acetophenones LANXESS DEUTSCHLAND GMBH (DE) 2001-06-28 — — US claimed
US-6184417-B1 DIAZOTATION OF A FLUOROALKYLANILINE; HEATING THE SALT SOLUTION WITH ACETALDOXIME IN THE PRESENCE OF A COPPER COMPOUND AND HALIDE IONS, WHERE NO BUFFER NOR REDUCING AGENT IS NEEDED; WATER POLLUTION CONTROL; KINETICS; EFFICIENCY BAYER AKTIENGESELLSCHAFT (DE) 2001-02-06 — — US claimed
JP-61024529-A — — None — — JP disclosed
CN-115559119-B Multifunctional super-hydrophobic fabric and preparation method thereof 苏州大学 2024-07-05 — — CN disclosed
WO-2023213028-A1 MULTIFUNCTIONAL SUPER-HYDROPHOBIC FABRIC AND PREPARATION METHOD THEREFOR 苏州大学 2023-11-09 — — WO disclosed
WO-2023044685-A1 HIGH-THROUGHPUT OIL-WATER SEPARATION COMPOSITE METAL MESH, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 苏州大学 2023-03-30 — — WO disclosed
WO-2016183101-A1 PALLADIUM-CATALYZED ARYLATION OF FLUOROALKYLAMINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-11-17 — — WO disclosed
US-4873027-A INTERMEDIATES FOR N-FLUOROALKYLANILINE PRECURSORS FOR FLUORINE-CONTAINING DISPERSE AZO DYES SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-10-10 — — US disclosed
US-4873027-A INTERMEDIATES FOR N-FLUOROALKYLANILINE PRECURSORS FOR FLUORINE-CONTAINING DISPERSE AZO DYES SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-10-10 — — US disclosed
EP-0171205-B1 FLUOROALKYLARYLIODONIUM COMPOUNDS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-04-20 — — EP disclosed
EP-0171205-A1 Fluoroalkylaryliodonium compounds SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-02-12 — — EP disclosed
EP-0171205-A1 Fluoroalkylaryliodonium compounds SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-02-12 — — EP disclosed
JP-S6124529-A FLUOROALKYLARYLIODONIUM COMPOUND SAGAMI CHEM RES CENTER 1986-02-03 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093534-A1 FLUORALKYLPHENYLAMIDINES AND THE USE THEREOF AS FUNGICIDES PFAS, DDT, PAH TDP1 680/4885ALDH1A1 526/4885TSHR 2892/4885
US-20010005767-A1 Process for the preparation of poly(fluoroalkyl)acetophenones DDT, DDC, AGPS TDP1 4164/4885ALDH1A1 69/4885TSHR 3741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.