Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350755 | 0.73 | TDP1 (0.56) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL646260 | 0.73 | TDP1 (0.44) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL8516545 | 0.73 | TDP1 (0.44) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL4964227 | 0.73 | TDP1 (0.44) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL3337536 | 0.73 | TDP1 (0.44) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL4892692 | 0.73 | TDP1 (0.44) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL27337982 | 0.73 | TDP1 (0.56) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL5440741 | 0.71 | TDP1 (0.43) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL15826348 | 0.71 | TDP1 (0.43) | TDP1ALDH1A1TSHRHSD17B10ALOX15 | |
| SCHEMBL28558650 | 0.69 | TDP1 (0.64) | TDP1ALDH1A1TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1825883-B1 | Agents for coloring keratin fibers | PROCTER & GAMBLE (US) | 2010-04-14 | — | — | EP | disclosed |
| US-7658771-B2 | Coloring agents for keratin fibers | THE PROCTER & GABLE COMPANY (US) | 2010-02-09 | — | — | US | disclosed |
| US-7658770-B2 | Agents for coloring keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2010-02-09 | — | — | US | disclosed |
| US-20090165221-A1 | Agents for Coloring Keratin Fibers | WELLA OPERATIONS US, LLC | 2009-07-02 | — | — | US | disclosed |
| US-20090158532-A1 | For the simultaneous lightening and coloring of keratin fibers; oxidizing agent and azo dye such as 2-[{4-[(4,5-dimethyl-1,3-thiazol-2-yl) diazenyl ]phenyl}(ethyl)amino]-N,N,N-trimethylethanaminium bromide | WELLA OPERATIONS US, LLC | 2009-06-25 | — | — | US | disclosed |
| US-7513916-B2 | Agents for coloring keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-07 | — | — | US | disclosed |
| US-7513917-B2 | Coloring agents for keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-07 | — | — | US | disclosed |
| US-20070199160-A1 | Agents for coloring keratin fibers | THE PROCTER & GAMBLE COMPANY | 2007-08-30 | — | — | US | disclosed |
| WO-2007097930-A1 | AGENTS FOR COLORING KERATIN FIBERS | THE PROCTER & GAMBLE COMPANY (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20070199161-A1 | Coloring agents for keratin fibers | WELLA OPERATIONS US, LLC | 2007-08-30 | — | — | US | disclosed |
| EP-1825883-A1 | Agents for coloring keratin fibers | Wella Aktiengesellschaft (DE) | 2007-08-29 | — | — | EP | disclosed |
| WO-2007093943-A1 | COLORING AGENTS FOR KERATIN FIBERS | THE PROCTER & GAMBLE COMPANY (US) | 2007-08-23 | — | — | WO | disclosed |
| EP-1820536-A1 | Coloring agents for keratin fibers | Wella Aktiengesellschaft (DE) | 2007-08-22 | — | — | EP | disclosed |
| EP-1820537-A1 | Agents for coloring keratin fibers | Wella Aktiengesellschaft (DE) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090165221-A1 | Agents for Coloring Keratin Fibers | KRT18, IK, KRTCAP2 | TDP1 3306/4885ALDH1A1 1069/4885TSHR 4808/4885 |
| US-20090158532-A1 | For the simultaneous lightening and coloring of keratin fibers; oxidizing agent and azo dye such as 2-[{4-[(4,5-dimethyl-1,3-thiazol-2-yl) diazenyl ]phenyl}(ethyl)amino]-N,N,N-trimethylethanaminium bromide | KRT18, TPM4, TUBB1 | TDP1 2747/4885ALDH1A1 243/4885TSHR 3917/4885 |
| US-20070199161-A1 | Coloring agents for keratin fibers | KRT18, IK, KRTCAP2 | TDP1 3288/4885ALDH1A1 1070/4885TSHR 4824/4885 |
| US-20070199160-A1 | Agents for coloring keratin fibers | KRT18, IK, KRTCAP2 | TDP1 3306/4885ALDH1A1 1069/4885TSHR 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.